The Use of Green Inhibitors in Evaluating the Safe Expiry Dates of Therapeutics

Abstract

The present work was done with dual intentions. The primary aim was to attenuate the acid corrosion of 6061 aluminum alloy by green approach. While doing so, an attempt was made to use the expiry date pharmaceutical product Streptomycin (SEPT) injection. This unique method could provide the best possible pathway for the utility of otherwise useless, non-eco-friendly expiry date drugs. Corrosion inhibition studies were performed using electrochemical techniques. Experimental settings were augmented to attain the highest possible efficacy of SEPT by changing its concentration and temperature. Experimental values were close-fitted into proper adsorption isotherm. Surface morphology studies like SEM and AFM were performed to confirm the adsorption of inhibitor. Streptomycin emerged as an exceptionally good inhibitor with an efficacy of 77% for the addition of just 1 ppm of the inhibitor at 303 K. Outcome of the work provided a unique pathway for utility expiry date drug, thereby minimizing the environmental pollution.

Corrosion inhibition and thermodynamic studies on carbon steel in well water by ethanolic extract of Alpinia officinarum leaves (Lesser galangal)-Zn2+

“…2D AFM images were analyzed the roughness parameters of pure CS (uncorroded), CS submerged in well water (corroded) and CS submerged in a blank system (well water) with inhibitor systems (protected) are coordinated to visualize the smoother CS surface through the adsorption of inhibitor molecules (55,87,88) . Data of AFM parameters are shown in Table 14 .…”

Experimental and theoretical studies for corrosion of molybdenum electrode using streptomycin drug in phosphoric acid medium

“…Therefore, utilization of inhibitors to reduce corrosion of metals in contact with aggressive conditions is crucial, especially compounds containing N, S, or O 16 , 17 . A family of green corrosion inhibitors known as antibacterial medications has been proven to slow down the corrosion of engineered materials in a variety of media 18 .…”

“…Therefore, utilization of inhibitors to reduce corrosion of metals in contact with aggressive conditions is crucial, especially compounds containing N, S, or O 16,17 . A family of green corrosion inhibitors known as antibacterial medications has been proven to slow down the corrosion of engineered materials in a variety of media 18 .Streptomycin is a first-line medicine for the treatment of plague that is also frequently used to treat tuberculosis when combined with other medications 19 . With effective antibacterial action, an aminoglycoside antibiotic called streptomycin produced from Streptomyces griseus [20][21][22][23] with inhibitory consequence on Gram-negative bacteria, it is a well-known vet medication for bacterial illnesses and livestock farming 24 .…”