The use of I131 albumin tissue clearance measurements and other physiological tests for the clinical assessment of patients with lymphœdema

A Study on the Pathogenesis of Postmastectomy Lymphedema

“…Tissue clearance of 131I albumin was shown by the period to reach half value as much as the locally injected labeled albumin (Emmett et al 1967;Jepson et al . 1953;Taylor et al 1957).…”

The washout rate of a subcutaneous 99mTc‐HSA depot in lower extremity lymphoedema

“…The scintigraphies showed low-to absent activity uptake in epifascial lymphatic collectors and inguinal lymph nodes compared to a normal lymphoscintigraphy with 99m Tc-Nanocoll Ò (Fig. These results were subsequently confirmed by Langgård (1963) and later by Emmett et al (1967). A large amount of the injected activity was found in the blood pool and in the urinary system.…”

“…A large amount of the injected activity was found in the blood pool and in the urinary system. To our knowledge only Mostbeck & Partsch (1999) and Emmett et al (1967) have applied washout rate constants to lower extremity lymphoedema. Hollander et al (1961) was according to our knowledge the first to investigate the subcutaneous washout rate of 131 I-HSA.…”

Measurement of the Interstitial Pressure in Subcutaneous Tissue in Dogs

“…The apparently contradictory results of measuring the interstitial pressure, where measurements of venous pressure and measurements with a hypodermic needle usually but not always (11) give slightly positive values and measurements with capsule or cotton thread give negative values, can thus be explained by the above assumption.…”