The use of laser doppler flowmetry to evaluate anterior cruciate blood flow

Schlehr, Frank J.; Limbird, Thomas A.; Swiontkowki, Marc F.; Keller, Tony S.

doi:10.1002/jor.1100050120

Cited by 31 publications

(17 citation statements)

References 6 publications

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“…[2][3][4]16,24,25,28 LDF depends on the doppler shift occurring when monochromatic light is scattered by moving blood cells. Studies by Astrom confirmed that this technology can be used to study blood flow in human Achilles' tendon.…”

mentioning

confidence: 99%

Arthroscopic suture bridge transosseus equivalent fixation of rotator cuff tendon preserves intratendinous blood flow at the time of initial fixation

Christoforetti¹,

Krupp

Singleton

et al. 2012

Journal of Shoulder and Elbow Surgery

108

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mentioning

confidence: 99%

Arthroscopic suture bridge transosseus equivalent fixation of rotator cuff tendon preserves intratendinous blood flow at the time of initial fixation

Christoforetti¹,

Krupp

Singleton

et al. 2012

Journal of Shoulder and Elbow Surgery

108

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“…temporary ischemia have been inadequately studied because of the nature of microsphere estimations; a limit of six data points are available and these must be separated by minutes to allow collection of reference organ blood (18,19). Similarly, clearance of bone-seeking isotopes is hampered by a n even more restricted number of data points (5).Laser Doppler flowmetry (LDF) has been utilized extensively in our laboratory over the past 5 years as a method for studying bone, ligament, and meniscus perfusion (12,13,(15)(16)(17)(18). Recently, we documented the reproducibility of LDF in an in vitro bone perfusion chamber (1,10,1 I).…”

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confidence: 99%

Cortical bone microperfusion: Response to ischemia and changes in major arterial blood flow

Swiontkowski

Senft

1992

Journal Orthopaedic Research

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In order to investigate the effects of short-term ischemia on cortical bone microperfusion, an isolated porcine tibia diaphyseal preparation based on intact nutrient vessels was developed. Laser Doppler flowmetry (LDF) was utilized to assess continuously the cortical microcirculation and the response to short-term ischemia. The femoral artery was isolated and clamped to develop the condition of bone ischemia. On release of the clamp, reactive hyperemia was documented in all animals. Using a roller pump connected to a segment of femoral artery, the same preparation was utilized to investigate the effect of a changing femoral artery flow on the cortical microcirculation. A positive correlation between LDF output and change in arterial inflow (r = 0.64) was defined. This model has the potential for studying the effect of ischemia on bone cell viability.

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“…Swiontkowski et al [13] used LDF to measure the blood flow in bone and meniscus. Schlehr et al [12] and Pässler et al [11] also used LDF to evaluate the ACL blood flow. They stated that it may be used to assess the viability of anterior substitutes used in various reconstructive procedures without sacrificing ligamentous integrity.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, laser Doppler flowmetry (LDF) has been used to measure the blood flow within capillary beds and has proven to be useful in the clinical and experimental evaluation of blood flow in skin, ligament, and bone [8,[10][11][12][13][14]. The purpose of this study was to evaluate the usefulness of LDF in direct in vivo measurement of the reconstructed ACL's blood flow in the human knee.…”

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confidence: 99%

Blood flow measurement in reconstructed anterior cruciate ligaments using laser Doppler flowmetry

Yamagishi

Fujii

Roppongi

et al. 1998

Knee Surgery, Sports Traumatology, Arthroscopy

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Laser Doppler flowmetry (LDF) was used to measure blood flow in anterior cruciate ligaments (ACL) reconstructed using a bone-patellar tendon-bone autograft. Thirty-five patients (17 men, 18 women) undergoing second-look arthroscopy for a reconstructed ACL were selected at random for postoperative participation in the study at 6, 12, and 18 months. Eight patients with an intact ACL had their blood flow measured arthroscopically for a control. Under arthroscopic visualization, a 3 mm probe was placed through a trocar sleeve into the ACL. Functional flow was evaluated using LDF, for which the output signal, the blood cell flux (BCF), is expressed in terms of volts. These patients also underwent magnetic resonance imaging (MRI); MRI, IKDC final evaluation, and second-look arthroscopic findings for each patient were compared with the others. In normal ACL, the BCF value ranged from 120 to 130 mV, and synovial blood flow, 90-132 mV. Significantly high BCF values for the reconstructed ACL were noted at 6 and 12 months, but there was no change in synovial BCF postoperatively. There was a gradual return to near normal BCF values for the reconstructed ACL 18 months after surgery. Significantly abnormal BCF values (580 +/- 20 mV) were seen in cases with a severely abnormal IKDC final evaluation; there were few differences in BCF values between normal, nearly normal, and abnormal. LDF is easy to use and appears to be a reproducible technique for evaluating blood flow in the reconstructed ACL, offering distinct advantages for evaluating its maturation. Six months after surgery, there was a decrease in MRI with a high signal intensity, whereas the BCF values in the reconstructed ACL generally needed 18 months to return to near normal; the return was gradual. We believe the blood supply of the reconstructed ACL may originate from the synovium of posterior joint capsule within 6 months after surgery.

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The use of laser doppler flowmetry to evaluate anterior cruciate blood flow

Cited by 31 publications

References 6 publications

Arthroscopic suture bridge transosseus equivalent fixation of rotator cuff tendon preserves intratendinous blood flow at the time of initial fixation

Arthroscopic suture bridge transosseus equivalent fixation of rotator cuff tendon preserves intratendinous blood flow at the time of initial fixation

Cortical bone microperfusion: Response to ischemia and changes in major arterial blood flow

Blood flow measurement in reconstructed anterior cruciate ligaments using laser Doppler flowmetry

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