The Use of N-Butyl Cyanoacrylate Adhesive in the Closure of Mucoperiosteal Flap After the Surgical Extraction of Impacted Mandibular Third Molar

El-rewainy, Mahmoud A; Osman, Saeeda M.; Hassan, Nagy E.

doi:10.21608/adjalexu.2015.59139

Cited by 14 publications

(28 citation statements)

References 22 publications

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“…We believe that this is likely due to the bacteriostic effect of N2BCA. On the other hand; mild inflammatory cells were noticed on the control group, We refer this to the plaque induced gingivitis that developed from the food accumulation (El-rewainy et al, 2016). Regarding inflammatory reaction in the intramedullary space, there was no significant difference between the two groups.…”

Section: Discussionmentioning

confidence: 82%

Evaluation of N 2-butyl cyanoacrylate adhesive material in the fixation of dentoalveolar mandibular fractures in dogs

El-Sayed¹,

Hassan²,

Ragab³

et al. 2016

J. Dent. Oral Hyg.

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The prevalence of dentoalveolar fracture is usually seen among children and adolescents boys, 3 times more than girls that is due to its etiology, namely road traffic accident (minor accident), child abuse, and fall from high or epileptic seizures. It may occur as an isolated clinical entity or in conjunction with any other bone fracture. Bone adhesive to hold these fractures would be of great benefit. Recently N2 butylcyanoacrylate is being clinically used with minimal complications. The study is aimed at evaluating the efficacy of N2 butylcyanoacrylate adhesive material in the fixation of dentoalveolar mandibular fractures. 6 adults mongrel dogs 12 to 24 months old, weighting 9 to13 kg on average were used in this study. Dogs were anesthetized. A full mucoperiosteal flaps were raised on the premolar area; two vertical 1 cm osteotomies were carried out mesial and distal joined with a horizontal one. Few drops of N2-Butylcyanoacrylate (N2BCA) Histoacryl were applied to fix the fracture; on the left side the fractures were fixed conventionally with circumdental wire. Suturing is done on both sides. Despite of the slow healing rate at the N2BCA site both groups showed an uneventful healing that is free of inflammation and displacement. Both methods showed similar results; we claim that N2 butylcyanoacrylate is an alternative to circumdental wiring in fixation of dentoalvolar fractures.

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Section: Discussionmentioning

confidence: 82%

Evaluation of N 2-butyl cyanoacrylate adhesive material in the fixation of dentoalveolar mandibular fractures in dogs

El-Sayed¹,

Hassan²,

Ragab³

et al. 2016

J. Dent. Oral Hyg.

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“…Однак при використанні тканинного адгезиву не завжди можливо виконати з'єднання тканин в анатомо-топографічних ділянках, що схильні до динамічних рухів. Зустрічаються випадки алергічних реакцій, лімітацією для широкого використання є висока вартість тканинного адгезиву [13][14][15][16].…”

Section: сучасна стоматологія 2/2021unclassified

Evaluation of early healing of postoperative wounds oral mucosa depending on the method of hemostasis and connection of wound edges

Pavlenko¹,

Boiko²,

Kabanchuk³

2021

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Actuality. The final and obligatory stage of each surgical intervention in the oral cavity is the tight connection of the wound edges and ensuring quality hemostasis, in order to prevent postoperative complications and the fastest recovery of tissues. The literature describes various techniques for joining soft tissues, using suture material, staples, fabric adhesive compositions, but due to the emergence of new methods, it is important to compare them. Goal. Compare and evaluate the early stage of healing of postoperative wounds in the oral cavity after open alveolectomy and the use of three methods for hemostasis and connection of wound edges (high-frequency electric welding, suturing nylon 5/0 and N-butyl-2-cyanoacrylate medical adhesive composition). Materials and methods. The study involved 42 patients aged 56 to 83 years, who were in the stage of surgical preparation for prosthetics with removable dentures and required open alveolectomy. Patients with cognitive impairment, cancer, systemic disease, recent acute or long-term chronic cardiovascular and musculoskeletal disorders did not participate in the study. All patients who participated in the study were randomly divided into 3 groups according to the methods of hemostasis and connection of the wound edges. After performing an open alveolectomy, hemostasis and joining of the wound edges were performed. In group 1 (electric welding) consisting of 14 patients, hemostasis and connection of wound edges were performed by welding soft tissues with the device «EKVZ-300M1». In group 2 (suturing) consisting of 14 patients, hemostasis of the wound was performed by connecting its edges with suture material nylon 5/0. In group 3 (adhesive composition) consisting of 14 patients, hemostasis of the wound was performed by joining its edges with a synthetic N-butyl-2-cyanoacrylate medical adhesive composition. Assessment of pain in patients of each group was performed according to the visual-analog scale (VAS). Determination of postoperative wound healing was performed on the basis of the wound healing index according to Landry, Turnbull and Howley. The average time to achieve intra-wound hemostasis and connection of wound edges in each of the groups were determined. The average values of the length of the trapezoidal section in each of the groups were also determined. Results. The analysis of the obtained results showed statistically significant differences (p ≤ 0.05) on the first day in terms of pain sensitivity between groups 2 (sutures) and 3 (glue). On the third day on both indicators (pain and wound healing) between groups 2 and 3 there were no statistically significant differences (p > 0.05). Group 1 (electric welding) has no statistically significant differences in pain sensitivity for the first day with other groups (p > 0.05). Statistically significant differences (p ≤ 0.01) appear on the third day both in terms of pain sensitivity and in terms of wound healing. Conclusions. The method of high-frequency electric welding can be used for intra-wound hemostasis with almost simultaneous connection of the wound edges after open alveolectomy. We found that electric welding has better hemostatic properties, faster connection of wound edges, reduced surgical time, postoperative pain and better results of wound healing compared to suture and adhesive methods. The method of high-frequency electric welding can be an alternative to suture and adhesive methods of hemostasis and joining the edges of the wound oral mucosa after open surgery on the jaws. Key words: oral cavity, mucous membrane, high-frequency electric welding, nylon sutures, adhesive composition, hemostasis, connection, index assessment, oral surgery.

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“…Due to the ambiguous views of specialists and the development of the chemical industry as an alternative to the suture technique, a medical adhesive composition was created, which facilitated the work of surgeons [12,13]. However, it is not always possible to connect tissues in anatomical and topographic areas that are prone to dynamic movements [14,15]. There are some allergic reactions cases [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

“…There are some allergic reactions cases [16][17][18]. The limit for widespread usage is the high price of fabric adhesive [14].…”

Section: Introductionmentioning

confidence: 99%

Histotopographic and morphometric characteristics of the oral mucosa postoperative wounds healing, depending on the method of connecting the wound edges

et al. 2021

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Implementation of high-quality tissue connections and hemostasis in oral surgery is an urgent problem of modern dentistry, due to the lack of available universal methods that would help to facilitate the work of oral surgeon and reduce wound healing time. The aim of the research. To investigate and study the regeneration processes in the oral mucosa after high-frequency electric welding, suturing and medical adhesive composition. Materials and methods. This study compared the effect of three connection methods and hemostasis: high-frequency electric welding (EKVZ-300M1 “PATONMED®”, Ukraine), suture method (nylon 5/0 “PIRUS®”, China), adhesive composition (“Histoacryl®”, Germany). 72 rabbits were involved in experiment. An incision of the soft tissues of the vestibulum of the oral cavity of the maxilla with a length of 1.3–1.5 cm was made. On days 3, 7, 14 and 21, tissue samples were excised, histological and morphometric examination of the material were performed. Results. By statistical data processing of 72 rabbits was found that the reliability of differences in the levels of morphometric parameters between groups on each day is very high, as evidenced by the calculated values of the U-test. In 38 cases (90.5 %), the significance level was p≤0.01, in the other 4 cases – p≤0.05. The lowest value level of neutrophilic granulocytes was in rabbits of group No.1 (electric welding). In rabbits of group No. 1 GFBC were not observed in the 8 fields of view throughout the experiment. Conclusions. High-frequency electric welding of soft tissues can be used for effective intraoperative hemostasis and connection of the intraoral wound edges. Due to the absence of a foreign body (adhesive masses, filaments) and moderate alterative effect, histological examination indicates accelerated activation of regenerative processes in the early stages of observation in rabbits of group No. 1.

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The Use of N-Butyl Cyanoacrylate Adhesive in the Closure of Mucoperiosteal Flap After the Surgical Extraction of Impacted Mandibular Third Molar

Cited by 14 publications

References 22 publications

Evaluation of N 2-butyl cyanoacrylate adhesive material in the fixation of dentoalveolar mandibular fractures in dogs

Evaluation of N 2-butyl cyanoacrylate adhesive material in the fixation of dentoalveolar mandibular fractures in dogs

Evaluation of early healing of postoperative wounds oral mucosa depending on the method of hemostasis and connection of wound edges

Histotopographic and morphometric characteristics of the oral mucosa postoperative wounds healing, depending on the method of connecting the wound edges

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