The value of serum mean platelet volume in testicular torsion

Abstract

Objective: To compare the serum mean platelet volume (MPV) in patients with testicular torsion and healthy control subjects. Methods: This retrospective study compared clinical and demographic data from patients who underwent surgery for testicular torsion and healthy controls. Testicular torsion was diagnosed with a physical examination and Doppler ultrasonography. Age, leukocyte count, platelet count and MPV were recorded for all participants. Results: A total of 50 patients with testicular torsion and 51 healthy control subjects were enrolled. There was no significant difference in age and platelet count between the two groups. Patients with testicular torsion had a significantly higher leukocyte count and MPV, compared with controls. According to receiver operating characteristic curve analysis performed for the prediction of testicular torsion, the best cut-off point for MPV was 7.7 fl (sensitivity 62%, specificity 96%), and the best cut-off point for leukocyte count was 9.5 Â 10 9 /l (sensitivity 58%, specificity 80%). Conclusions: The MPV may be useful as an ancillary test for the diagnosis of testicular torsion. Further studies are needed in order to confirm these preliminary results.

Can haematologic parameters be used to predict testicular viability in testicular torsion?

“…Numerous studies have reported that haematologic parameters can be used for the differential diagnosis of TT (Bitkin et al, ; Cicek, Togan, Akbaba, Narci, & Aygun, ). But to our knowledge, only one study by Jang et al have reported the association between haematologic parameters and the testicular salvage rate.…”

“…Whether MPV can be used to diagnose TT remains controversial. Cicek et al, () retrospectively analysed MPV in 50 children with TT and 51 normal children and found that MPV had some diagnostic value for TT. In contrast, Güneş et al, () reported that MPV did not have diagnostic ability for TT, but NLR did, by comparing 75 TT patients with 56 age‐matched healthy subjects.…”

The role of inflammatory markers in decreasing negative appendectomy rate: a study based on computed tomography findings

“…[14] Several studies have evaluated the diagnostic value of MPV in AA; nevertheless, some of them advocate for an increase, while some others advocate for a decrease, in MPV levels. RDW is a measure of the variability of red blood cell size and has been shown to predict various inflammatory conditions.…”

Predictive value of ischaemia‐modified albumin in spermatogenesis in an experimental testicular torsion model

“…Cicek et al studied serum mean platelet volume (Cicek, Togan, Akbaba, Narci, & Aygun, 2015), Turedi et al studied plasma SCUBE-1 levels (Turedi et al, 2015), and Yilmaz et al studied plasma d-dimer levels . Cicek et al studied serum mean platelet volume (Cicek, Togan, Akbaba, Narci, & Aygun, 2015), Turedi et al studied plasma SCUBE-1 levels (Turedi et al, 2015), and Yilmaz et al studied plasma d-dimer levels .…”

“…Several studies have been performed to identify biomarkers for testicular torsion. Cicek et al studied serum mean platelet volume (Cicek, Togan, Akbaba, Narci, & Aygun, 2015), Turedi et al studied plasma SCUBE-1 levels (Turedi et al, 2015), and Yilmaz et al studied plasma d-dimer levels . IMA is caused by reactive oxygen derivatives resulting from ischaemia-modifying albumin (Can & Yosunkaya, 2017).…”