The viral aetiology of acute encephalitis in children in Vietnam

Tan, Le Van; Qui, Phan Tu; Doorn, H. Rogier van; Ha, Do Quang; Hien, Vo Minh; Bach, Van Cam; Khanh, Truong Huu; Hue, Nguyen Bach; Hien, Tran Tinh; Châu, Nguyễn Văn Vĩnh; Nga, Tran Vu Thieu; Schultsz, Constance; Farrar, Jeremy; Jong, Menno D. de

doi:10.1186/1753-6561-2-s1-p67

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“…In our study, the mean age of presentation was 4.6 years, which is consistent with Kamble, who documents 1-5 years as the most common age of presentation 7 . Tan L V et al, in his study reported 4.5 years as the mean age of children with Acute Encephalitis 10 . In a study by Hsieh W B three fifth of the children with encephalitis were below the age of 6 years.…”

Section: Discussionmentioning

confidence: 89%

“…A delayed, incorrect or insufficient treatment would result in mortality and irreversible sequlae. Suspected cases should be started on Aciclovir, which has revolutionized the treatment of viral encephalitis is, lowering mortality from 70% to between 6-19% 5,10,11 . Neuromonitoring through EEG helps a lot in predicting the course of the disease.…”

Section: Introductionmentioning

confidence: 99%

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To Study the Electroencephalogram Changes in Children with Acute Encephalitis

Ali¹,

Hussain²

2021

PJMHS

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Aim: To study the electroencephalogram changes in children with acute encephalitis. Study design: Cross-sectional study. Place and duration of study: The cases were admitted from OPD and emergency over duration of 10 months from May2009 to March 2010 in Children Hospital PIMS, Islamabad. Method: Patients with Cerebral Palsy, Degenerative Brain disease, Cerebral Malaria and Meningitis were excluded. Written informed consent was taken from parents /guardians. All patients, from both genders, age varying from 4 months to 12 years, fitting the criteria of Acute Encephalitis according to ICD 9 & 10 were included in the study, which were 56 in total. All cases had Lumbar puncture and Cerebro Spinal Fluid examination. The findings of pleocytosis (WBC count more than5 u/l), protein and sugar were recorded. EEG (Electroencecephlogram) was done in 52 patients, frequencies and percentages were calculated of the findings. Results: The mean age was 4. 6 years, (varying from 4 months to 12 years) with a standard deviation of 3. 2. From a total of fifty six patients, 38(68%) were males and 18(32%) females. All cases presented with fever (100%). Cerebro Spinal Fluid examination, showed Pleocytosis in 30(54%) while 46(46%) had normal cell count. Cerebro Spinal Fluid protein content was normal in 45(80%) and increased in 11(20%). Cerebro Spinal Fluid sugar was normal in 50(89%) and 6(11%) had low. Electroencephalogram was done in fifty-two patients out of which 30(58%) were normal, 22(42%) were abnormal. Intermittent slowing was found in 17(77%) and 5(23%) cases had focal discharges along with intermittent slowing, out of which three were unilateral temporo-frontal discharges, two cases had other focal discharges on EEG. Conclusion: In patients with Acute Encephalitis, slowing of the rhythm was the most frequent abnormal Electroencephalogram finding, followed by focal discharges in children admitted in Children’s Hospital PIMS, Islamabad. Keywords: Acute Encephalitis, Electroencephalogram (electro encephalogram), Cerebro Spinal Fluid Pleocytosis, Fever

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Section: Discussionmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%