IN a previous communication [Macrae et at. 1939] we described the preparation from liver extracts of highly potent concentrates of a nutritional factor for rats to which we applied the name "liver ifitrate factor" [cf. Edgar et al. 1938].; At that time we drew attention to the similarity in properties between this factor and pantothenic acid [Williams et al. 1938; 1939] and discussed the possibility that the two might ultimately prove to be identical. Pantothenic acid was then