Therapeutic Effects of Ribunucleinate (Ribonucleotides) in Immuno-Inflammatory and Arthritic Diseases

Stommel, G.; Schuehlein, S.; Schuehlein, K.-H.; Rainsford, K. D.

doi:10.1007/978-3-0348-0927-6_2

Cited by 2 publications

(1 citation statement)

References 165 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a typical example, biologically active substances known as a ribonucleic acid / ribonucleotide extract (RN preparations), derivatives of connective tissue of animals and yeast (Schroeder et al, 1989;Rainsford, 1996). Previously, similar RNA-containing substances were widely used in the complex therapy of various inflammatory syndromes, including arthritis (Stommel et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Osteoprotective Properties of RNA-Containing Drug Osteochondrin S on the Model of Insufficiency of Sex Hormones in Rats

et al. 2017

View full text Add to dashboard Cite

SHULGAU, Z.; SERGAZY, S.; KRIVORUCHKO, T.; KENZHEBAYEVA, N.; SAGINDYKOVA, B. & GULYAYEV, A.Osteoprotective properties of RNA-containing drug Osteochondrin S on the model of insufficiency of sex hormones in rats. Int. J. Morphol., 35(4):1233Morphol., 35(4): -1238Morphol., 35(4): , 2017. SUMMARY:The aim of the study was to evaluate the osteoprotective properties of RNA-containing drug Osteochondrin S on rats with experimental model of osteoporosis. Osteochondrin S contains yeast RNA and RNA of connective tissue of cattle. In order to model osteoporosis in rats bilateral ovariectomy was used. Rats were divided into 3 groups: 1 -ovariectomized rats receiving Osteochondrin S; 2 -ovariectomized rats receiving saline; 3 -sham-ovariectomized rats. Rats in group 1 received Osteochondrin S, Group 2 -physiological saline three times a week for 12 weeks. Based on morphological data and on the results of densitometry, Osteochondrin S prevents a decrease in bone density, i.e. exhibits osteoprotective properties. Under the condition of lack of sex hormones in rats Osteochondrin S reduces reactive oxygen species in blood plasma and limits the degree of decrease in antioxidant capacity of blood plasma.

show abstract

Section: Introductionmentioning

confidence: 99%

Osteoprotective Properties of RNA-Containing Drug Osteochondrin S on the Model of Insufficiency of Sex Hormones in Rats

et al. 2017

View full text Add to dashboard Cite

show abstract

Gonartrozlu Hastalarda Trigliserit Glikoz İndeksi ile Nötrofil Lenfosit Oranı Arasındaki İlişki

ERGENÇ¹,

Ergenç²,

OFLAZ³

2023

Sakarya Medical Journal

View full text Add to dashboard Cite

Aim: This study investigated the relationship between Triglyceride Glucose, Neutrophil Lymphocyte Ratio, and gonarthrosis disease to investigate the role of these indicators in developing gonarthrosis. Method: Our study retrospectively investigated 141 patients aged between 50-84 years old who underwent follow-up in our orthopedic clinic between 01.06.2022-01.10.2021. The participants were divided into two control and study groups. Participants diagnosed with gonarthrosis were included in the study group, and healthy controls were included in the control group. Demographic characteristics of the patients and biochemical data were collected from patient files and electronic records. Results: The age of the patients was 54±12.5 (18-75) years. Among the biochemical parameters in our study, in cases with fasting gallstones, plasma glucose is 124.6 ± 24.5 mg/dL, triglyceride 198.3 ± 36.8 mg/dL, insulin 16.5 ± 5.6 uIU/mL, HOMA-IR 4 The level of .8±1.2 was statistically significantly higher in all of them compared to the control group (p=0.001). TGYI shows a significant difference according to the group (p

show abstract

Therapeutic Effects of Ribunucleinate (Ribonucleotides) in Immuno-Inflammatory and Arthritic Diseases

Cited by 2 publications

References 165 publications

Osteoprotective Properties of RNA-Containing Drug Osteochondrin S on the Model of Insufficiency of Sex Hormones in Rats

Osteoprotective Properties of RNA-Containing Drug Osteochondrin S on the Model of Insufficiency of Sex Hormones in Rats

Gonartrozlu Hastalarda Trigliserit Glikoz İndeksi ile Nötrofil Lenfosit Oranı Arasındaki İlişki

Contact Info

Product

Resources

About