Thiosemicarbazones as Aedes aegypti larvicidal

Dibenzo-α-pyrones: a new class of larvicidal metabolites againstAedes aegyptifrom the endophytic fungusHyalodendriellasp. Ponipodef12

“…Similarly, the halogenated naphthoquinones were found to be more active against A. aegypti than those non‐halogenated congeners . Likewise, the larvicidal thiosemicarbazones and 1,2,4‐oxadiazoles exhibited stronger activities against A. aegypti when the para position of the phenyl group had a halogen substituent (Cl or Br, the latter being better). Thus further structural optimization of the dibenzo‐α‐pyrones, by introducing another halogen atom such as Br, or increasing the numbers of halogen substituents, might lead to the discovery of more larvicidal compounds with stronger effect.…”

Larvicidal Activities of 2-Aryl-2,3-Dihydroquinazolin -4-ones against Malaria Vector Anopheles arabiensis, In Silico ADMET Prediction and Molecular Target Investigation

“…In addition, insecticide resistance is becoming increasingly alarming and threatens the management of vectors, thereby leading to prioritizing the development of new potent and safer biologically active heterocyclic compounds as well as to aid in resistance management [4]. There are certain reports concerning the larvicidal activity of synthetic compounds [5][6][7][8][9][10][11][12].…”

Determination of the larvicidal activity of benzoyl thiosemicarbazone and its Ni(II) complex against Aedes aegypti and Anopheles darlingi larvae in Amazonas, Brazil

“…The pharmacological applications of the different structural derivatives of thiosemicarbazones and their metal complexes include antifungals (Parrilha et al, 2011), cytotoxics (Rebolledo et al, 2005;Braga et al, 2016), antibacterials (Despaigne et al, 2010), antimalarials (Greenbaum et al, 2004;Chellan et al, 2010;Nandal and Deep, 2017) and insecticides (Rayms-Keller et al, 1998;Wang et al, 2010;Silva et al, 2015). Metal complexes or even free metal ions are toxic to aquatic organisms and may be found available at low levels in the environment (Arnold et al, 2005).…”