Three‐dimensional CT angiography: A new technique for imaging microvascular anatomy

Abstract

To date there has been no satisfactory research method for imaging microvascular anatomy in three dimensions (3D). In this article we present a new technique that allows both qualitative and quantitative examination of the microvasculature in 3D. In 10 fresh cadavers (7 females, 3 males, mean age 68 years), selected arteries supplying the abdominal wall and back were injected with a lead oxide/gelatin contrast mixture. From these regions, 30 specimens were dissected free and imaged with a 16-slice spiral computed tomographic (CT) scanner. Using three-dimensional CT (3D-CT) angiography, reconstructions of the microvasculature of each specimen were produced and examined for their qualitative content. Two calibration tools were constructed to determine (1) the accuracy of linear measurements made with CT software tools, and (2) the smallest caliber blood vessel that is reliably represented on 3D-CT reconstructions. Three-dimensional CT angiography produced versatile, high quality angiograms of the microvasculature. Correlation between measurements made with electronic calipers and CT software tools was very high (Lin's concordance coefficient, 0.99 (95% CI 0.99-0.99)). The finest caliber of vessel reliably represented on the 3D-CT reconstructions was 0.4 mm internal diameter. In summary, 3D-CT angiography is a simple, accurate, and reproducible method that imparts a much improved perception of anatomy when compared with existing research methods. Measurement tools provide accurate quantitative data to aid vessel mapping and preoperative planning. Further work will be needed to explore the full utility of 3D-CT angiography in a clinical setting.

Reviewing the vascular supply of the anterior abdominal wall: Redefining anatomy for increasingly refined surgery

“…Although individual variability has been highlighted within the literature, patterns of supply have become evident, and the means to surgically overcoming anatomical challenges have been discussed. The technology to image these finer vessel branches both in cadavers and preoperatively will only further enhance our understanding of this area of vascular anatomy (Rozen et al, 2007c;Tregaskiss et al, 2007).…”

Three‐dimensional CT angiography: A new technique for imaging microvascular anatomy

“…We would like to congratulate Tregaskiss et al for their study utilizing computerized tomography angiography (CTA) for mapping the vasculature of the body wall (Tregaskiss et al, 2007). This is a significant contribution to the literature in this evolving field of anatomical research.…”

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