“…For living biological samples ranging from embryonic development studies all the way to neuroscience, it provides high resolution, contrast, specificity, penetration depth, and image acquisition speed, and has relatively low levels of phototoxicity and photobleaching [1][2][3][4][5] . For colloidal and granular materials, it allows particles to be tracked for study of soil mechanics 6,7 , flow behavior and rheology [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] , packing and jamming phenomena 7,21,22,24,25 . For all such applications, a sample is illuminated by a laser sheet, resulting in a two dimensional cross-sectional image, which can be combined into a stack of scanned images to obtain a threedimensional representation 26,27 .…”