Thyroid volume determination by single photon tomography and 3D processing for activity dose estimation

Lyra, Maria; Striligas, J.; Gavrilelli, M.; Chatzijiannis, C.; Skouroliakou, K.

doi:10.1109/ist.2008.4659932

Cited by 6 publications

(5 citation statements)

References 4 publications

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“…In previous studies, either water containers with hollow inserts down to 5 mL were used to simulate remnants [8][9][10] or neck-thyroid phantoms with hollow thyroid glands with or without other anatomical structures [12][13][14][15] were used in Tc-99m and I-131 SPECT studies. In this study, a neck-thyroid phantom with different sizes of small (0.5-10 mL) thyroid remnants at clinically relevant positions, including all relevant anatomical structures, and able to simulate different background-to-remnant activity ratios, was developed to specifically study postsurgical thyroid-remnant SPECT/CT imaging procedures.…”

Section: Discussionmentioning

confidence: 99%

“…For SPECT imaging, Tc-99m, I-131 or I-123 labelled radiopharmaceuticals can be employed, with I-123 being favorable because, unlike Tc-99m, it has the same physical characteristics as I-131, which is used for ablation, while avoiding the "stunning" effect [4] and lower image quality, which is observed when the latter is used [5][6][7]. These scans may be utilized for visual evaluation by physicians, estimation of remnant volume [8][9][10] and pre-ablation dosimetry [11] to further aid treatment decisions.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies [8][9][10] developed simple water containers with hollow cylindrical or spherical inserts down to 5 mL to simulate thyroid remnants. They utilized these phantoms to validate algorithms using Tc-99m SPECT images.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Neck-Thyroid Phantom with Small Sizes of Thyroid Remnants for Postsurgical I-123 and I-131 SPECT/CT Imaging

Michael

Hadjiconstanti

Lontos

et al. 2023

Life

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Post-surgical I-123 and I-131 SPECT/CT imaging can provide information on the presence and sizes of thyroid remnants and/or metastasis for an accurate re-staging of disease to apply an individualized radioiodine therapy. The purpose of this study was to develop and validate a neck–thyroid phantom with small sizes of thyroid remnants to be utilized for the optimization of post-surgical SPECT/CT imaging. 3D printing and molding techniques were used to develop the hollow human-shaped and -sized phantom which enclosed the trachea, esophagus, cervical spine, clavicle, and multiple detachable sections with different sizes of thyroid remnant in clinically relevant positions. CT images were acquired to evaluate the morphology of the phantom and the sizes of remnants. Triple-energy window scattered and attenuation corrected SPECT images were acquired for this phantom and for a modified RS-542 commercial solid neck–thyroid phantom. The response and sensitivity of the SPECT modality for different administered I-123 and I-131 activities within the equal-size remnants of both phantoms were calculated. When we compared the phantoms, using the same radiopharmaceutical and similar activities, we found that the measured sensitivities were comparable. In all cases, the I-123 counting rate was higher than the I-131 one. This phantom with capabilities to insert different small sizes of remnants and simulate different background-to-remnants activity ratios can be utilized to evaluate postsurgical thyroid SPECT/CT imaging procedures.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Neck-Thyroid Phantom with Small Sizes of Thyroid Remnants for Postsurgical I-123 and I-131 SPECT/CT Imaging

Michael

Hadjiconstanti

Lontos

et al. 2023

Life

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“…Avdal et al [32] estimate the flow volume by the maximum velocity in each voxel. Lyra et al [33] add transaxial slices to measure the thyroid volume of hyperthyroid patients. Yu et al [34] calculate the difference in the current depth image and reference depth image by splitting planes to estimate the volume of chest wall.…”

Section: Slicing Methodmentioning

confidence: 99%

Accurate Volume Calculation Driven by Delaunay Triangulation for Coal Measurement

Liu

Zheng

2021

Scientific Programming

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Volume calculation from 3D point cloud is widely used in engineering and applications. The existing methods either have large errors or are time-consuming. This paper focuses on the coal measurement. Based on the triangular mesh generated from the point cloud, each triangle is projected downward to the base plane to form a voxel. We derive the calculation formula of voxel by an integral method, which is more efficient than the method of decomposing voxel into tetrahedrons and more accurate than slicing methods. Furthermore, this paper proposes a Delaunay triangulation-driven volume calculation (DTVC) method. DTVC does not preserve the Delaunay triangles but directly calculates the volume in the process of triangulation. It saves memory and running time. Experimental results show that DTVC has achieved a good balance between error and efficiency.

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“…Thyroid Uptake Study is useful in the diagnosis and treatment of Hyperthyroidism. Apart from Tc-99m pertechnetate, other radiopharmaceuticals that are preferred are Iodine-123 (sodium iodide) given orally in administered activity of 200 to 400 microcuries (7.4 to 14.8 Mbq) [3] and Iodine-131 with an oral administration of 25 microcuries (0.92 Mbq). The rest of this paper is organized as follows.…”

Section: Introductionmentioning

confidence: 99%

An interactive GUI tool for thyroid Uptake studies using Gamma Camera

Subramaniyan

Rajamani

et al. 2014

2014 International Conference on Advances in Computing, Communications and Informatics (ICACCI)

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Thyroid uptake study is a technique that requires injection of a radio-isotope/radiotracer emitting gamma rays into the blood stream of the patient. Thyroid imaging is done by means of Thyroid Uptake imaging system. In the absence of a sophisticated system, imaging can also be done using Gamma Camera. By intravenously injecting 2 millicuries of Technetium-99m pertechnetate radio-isotope, serial thyroid images are acquired. This Uptake study provides Functional information and is useful for diagnosis and treatment of Hyperthyroidism. Thyroid uptake study done using Gamma Camera has to be calibrated at each laboratory using this technique. In our hospital it has been standardized that a tracer uptake of greater than 2 % is considered Hyperthyroidism, between 0.5 and 2 % is considered normal and less than 0.5 % is considered Hypothyroidism. Thyroid Uptake is calculated based on the counts. Counts are nothing but the sum of all intensities in the selected region of the image. Gamma Camera uses a LEAP (Low Energy All Purpose) collimator which handles only photons emitted from radioisotopes having lower emission energies. So Technetium-99m is used which has its energy of emission around 140 keV. For a typical Thyroid Uptake Probe where Iodine-131 having greater emission energy of 364 keV is preferred, existing Thyroid Uptake software cannot be used. Therefore an Interactive GUI (Graphical User Interface) tool was developed for thyroid Uptake studies using Fiji for determination of tracer uptake by manually drawing the ROI (Region of Interest) around left and right thyroid lobes separately. Developed tool was tested on 30 real time thyroid cases (26 female and 4 male) and the uptake values obtained are compared with those obtained from the existing software tool.Index Terms -Interactive GUI, Fiji, ROI, Anticubital, Radiotracer.

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Thyroid volume determination by single photon tomography and 3D processing for activity dose estimation

Cited by 6 publications

References 4 publications

A Neck-Thyroid Phantom with Small Sizes of Thyroid Remnants for Postsurgical I-123 and I-131 SPECT/CT Imaging

A Neck-Thyroid Phantom with Small Sizes of Thyroid Remnants for Postsurgical I-123 and I-131 SPECT/CT Imaging

Accurate Volume Calculation Driven by Delaunay Triangulation for Coal Measurement

An interactive GUI tool for thyroid Uptake studies using Gamma Camera

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