Time‐resolved contrast‐enhanced MR angiography with single‐echo Dixon fat suppression

Stinson, Eric G.; Trzasko, Joshua D.; Campeau, Norbert G.; Glockner, James F.; Huston, John; Young, Phillip M.; Riederer, Stephen J.

doi:10.1002/mrm.27152

Cited by 4 publications

(2 citation statements)

References 47 publications

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“…Moreover, the study has confirmed that the detection rate of CEUS combined with enhanced MR scanning was higher. The detection rate of lesions, localization accuracy, qualitative accuracy, and diagnostic coincidence rate in the experimental group are significantly better than those in the control group, which was similar to the results of [ 18 ]. Our results indicated that CEUS combined with enhanced MR scanning was more accurate and comprehensive in the diagnosis and differentiation of ICC.…”

Section: Discussionsupporting

confidence: 87%

Application Value of Contrast-Enhanced Ultrasound Combined with Enhanced MR Scanning in Patients with Intrahepatic Cholangiocarcinoma

Zhang

Liu

Han

et al. 2022

Journal of Healthcare Engineering

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Objective. To explore the clinical application effect of contrast-enhanced ultrasound (CEUS) combined with enhanced MR scanning in patients with intrahepatic cholangiocarcinoma (ICC). Methods. 90 patients with ICC admitted to Ganyu District People’s Hospital of Lianyungang City from June 2017 to June 2018 were selected as the research objects and randomly divided into control group and experimental group, with 45 cases in each group. The control group was tested by CEUS, and the experimental group was tested by CEUS combined with enhanced MR scanning. The test results of the two groups were compared, and the benign and malignant indicators of the two groups were detected. Results. The rate of lesion detection, accuracy of localization qualitative accuracy, and diagnosis coincidence rate of the experimental group were significantly better than those of the control group (p < 0.05). The lesion length, tube wall thickness, and enhancement ratio of triple-phase multislice CT scan of the experimental group were lower than the control group (p＜0.05). Conclusions. CEUS combined with enhanced MR scanning has high sensitivity and specificity and can significantly improve the accuracy of the detection results. It provides scientific and accurate scientific basis for clinical treatment and diagnosis of ICC, which is worthy of popularization and application.

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Section: Discussionsupporting

confidence: 87%

Application Value of Contrast-Enhanced Ultrasound Combined with Enhanced MR Scanning in Patients with Intrahepatic Cholangiocarcinoma

Zhang

Liu

Han

et al. 2022

Journal of Healthcare Engineering

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“…In a small pilot study of 8 healthy volunteers, Nezafat et al demonstrated significantly higher CNR and SNR in the coronary artery tree with Dixon water-fat separation than spectral presaturation with inversion recovery (SPIR) fat suppression at 3 T, even without IV contrast administration [33]. mDixon techniques have been proven useful in peripheral CMRA as well [38, 39]. In contrast, Börnert et al, found that SNR and CNR tended to drop in bSSFP sequences after gadolinium administration and suggested that fat-saturated images may be advantageous in demonstrating small epicardial vessel structures and tissue boundaries [20].…”

Section: Discussionmentioning

confidence: 99%

mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease

Kourtidou

Jones

Moore

et al. 2019

Journal of Cardiovascular Magnetic Resonance

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Background Cardiovascular magnetic resonance (CMR) angiography (CMRA) is an important non-invasive imaging tool for congenital heart disease (CHD) and aortopathy patients. The conventional 3D balanced steady-state free precession (bSSFP) sequence is often confounded by imaging artifacts. We sought to compare the respiratory navigated and electrocardiogram (ECG) gated modified Dixon (mDixon) CMRA sequence to conventional non-gated dynamic multi-phase contrast enhanced CMRA (CE-CMRA) and bSSFP across a variety of diagnoses. Methods We included 24 patients with CHD or aortopathy with CMR performed between September 2017 to December 2017. Each patient had undergone CE-CMRA, followed by a bSSFP and mDixon angiogram. Patients with CMR-incompatible implants or contraindications to contrast were excluded. The studies were rated according to image quality at a scale from 1 (poor) to 4 (excellent) based on diagnostic adequacy, artifact burden, vascular border delineation, myocardium-blood pool contrast, and visualization of pulmonary and systemic veins and coronaries. Contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR) and quantitative vascular measurements were compared between the two gated sequences. Bland-Altman plots were generated to compare paired measures. Results All scans were diagnostically adequate. Mean (SD) quality scores were 3.4 (0.7) for the mDixon, 3.2 (0.5) for the bSSFP and 3.4 (0.5) for the CE-CMRA. Qualitatively, the intracardiac anatomy and myocardium-blood pool definition were better in the bSSFP; however, mDixon images showed enhanced vessel wall sharpness with less blurring surrounding the anatomical borders distally. Coronary origins were identified in all cases. Pulmonary veins were visualized in 92% of mDixon sequences, 75% of bSSFP and 96% of CE-CMRA. Similarly, neck veins were identified in 92, 83 and 96% respectively. Artifacts prevented vascular measurement in 6/192 (3%) and 4/192 (2%) of total vascular measurements for the mDixon and bSSFP, respectively. However, the size of signal void and field distortion were significantly worse in the latter, particularly for flow and metal induced artifacts. Conclusion In patients with congenital heart disease, ECG gated mDixon angiography yields high fidelity vascular images including better delineation of head and neck vasculature and pulmonary veins and fewer artifacts than the comparable bSSFP sequence. It should be considered as the preferred strategy for successful CHD imaging in patients with valve stenosis, vascular stents, or metallic implants. Electronic supplementary material The online version of this article (10.1186/s12968-019-0554-3) contains supplementary material, which is available to authorized users.

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An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom

Hormuth

Easley

et al. 2021

Medical Image Analysis

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Time‐resolved contrast‐enhanced MR angiography with single‐echo Dixon fat suppression

Abstract: Time-resolved contrast-enhanced MRI with single-echo Dixon fat suppression shows high image quality, improved vessel delineation, and reduced sensitivity to motion when compared to time-subtraction methods.

Cited by 4 publications

References 47 publications

Application Value of Contrast-Enhanced Ultrasound Combined with Enhanced MR Scanning in Patients with Intrahepatic Cholangiocarcinoma

Application Value of Contrast-Enhanced Ultrasound Combined with Enhanced MR Scanning in Patients with Intrahepatic Cholangiocarcinoma

mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease

An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom

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