TiO2 anchored carbon fibers as non-invasive electrochemical sensor platform for the cortisol detection

Madhu, Sekar; Ramasamy, Sriramprabha; Manickam, Pandiaraj; Ponpandian, N.; Viswanathan, C.

doi:10.1016/j.matlet.2021.131238

Cited by 22 publications

(12 citation statements)

References 10 publications

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“…[62][63][64][65][66][67][68][69][70][71][72][73][74][75][76][77] The performance of a given wearable device depends upon numerous parameters interwoven within the mechanical, electrical, and functional properties of the sensor. Designing a high-performance wearable sensorcharacterized by high sensitivity, selectivity, and stabilitynecessitates careful optimization of the means of biorecognition (e.g., enzyme/substrate, [78][79][80] antibody/antigen, [81,82] functional materials/biomarkers [83,84] ), method of signal transduction (e.g., optical, [85] electrochemical [86,87] ), and approach for transmitting the signal to the user. The device form factor (e.g., thickness, curvature, geometry) is equally critical as it governs the degree of conformity with the human body.…”

Section: Overview Of Additive Manufacturing Methodsmentioning

confidence: 99%

Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring

Yin,

Clark,

Ray

2023

Advanced Sensor Research

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Persistent disparities exist in access to state‐of‐the‐art healthcare disproportionately affecting underserved and vulnerable populations. Advances in wearable sensors enabled by additive manufacturing (AM) offer new opportunities to address such disparities and enhance equitable access advanced diagnostic technologies. Additive manufacturing provides a pathway to rapidly prototype bespoke, multifunctional wearable sensors thereby circumventing existing barriers to innovation for resource‐limited settings imposed by the need for specialized facilities, technical expertise, and capital‐intensive processes. This review examines recent progress in the additive manufacture of wearable platforms for physiological health monitoring. Supported by an initial overview of relevant techniques, representative examples of 3D printed wearable sensors highlight the potential for measuring clinically‐relevant biophysical and biochemical signals of interest. The review concludes with a discussion of the promise and utility of additive manufacturing for wearable sensors, emphasizing opportunities for expanding access to vital healthcare technology and addressing critical health disparities.

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Section: Overview Of Additive Manufacturing Methodsmentioning

confidence: 99%

Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring

Yin,

Clark,

Ray

2023

Advanced Sensor Research

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“…Alternative surface electrode materials include indium tin oxide (ITO), graphene, derivatives of graphene such as graphene oxide (GO), reduced graphene oxide (rGO), derivatives of carbon, such as glassy carbon, carbon nanotubes (CNTs), and carbon yarns. While CNTs have been used due to their superior electrical properties and mass production, conductive carbon yarns (CCY) have shown potential for integration with fabrics to achieve flexible wearable immunosensing platforms, in addition to high electrical conductivity and low production cost [35], [36], [37], [38]. Conductive thread textiles have also been utilized for their flexibility, lightweight, and size [39].…”

Section: A1 Sensor Structurementioning

confidence: 99%

“…The electrostatic attraction occurs because of the difference in isoelectric points (IEPs) of ZnO (9.5) and antibodies (4.5), which provides ZnO with positively charged surfaces for the adsorption of negatively charged antibodies. Other metal oxide nanostructures used in cortisol immunosensors were iron (III) oxide (Fe2O3) (IEP: 8.5) [35] and titanium dioxide (TiO2) (IEP: ~6.5) [37]. Tin sulfide (SnS2) [43] nanoflakes and molybdenum disulfide (MoS2) [44] were additional semiconductor nanostructures used for their high carrier mobility, low cost, and good chemical stability.…”

Section: A1 Sensor Structurementioning

confidence: 99%

Electrochemical Sensors for Cortisol: A Review

Naeem,

Guldin,

Ghoreishizadeh

2024

IEEE Sensors J.

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Cortisol, also known as the "stress hormone", is secreted under the control of the hypothalamic-pituitary-adrenocortical (HPA) axis in response to psychobiological stress. Real-time and continuous monitoring of the cortisol levels throughout the day can provide the information necessary to identify any abnormalities in cortisol's circadian rhythm that may disrupt the several processes that cortisol is involved in in the body. This review presents a systematic search of the literature on electrochemical cortisol sensing techniques that allow real-time measurement of cortisol in human biofluids. Several structural and performance-related parameters of sensors are being discussed, including the sensor stack layers, limit of detection (LoD), dynamic range, sensitivity, selectivity, reusability, redox probe usage, and the electrochemical detection technique used. The sensors here are primarily categorized based on the type of bioreceptors used: antibodies, molecularly imprinted polymers (MIPs), and aptamers. According to this review, cortisol aptasensors and the MIP-based sensors present, in general, superior stability and sensitivity over immunosensors. They also promise reversible binding, albeit limited research exists on sensors deploying such bioreceptors. Additionally, notable advancements in the field and their impact on the development of point-of-care (PoC) and wearable devices are discussed.

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“…In addition to integrating 1D fiber or 2D cloth conductors into the fabric by stitching, weaving, etc., textile-based electrodes can also be directly prepared into conductors through photolithography and screen printing, and other methods to get different shapes of conductors on the fabric [47,48] . There are many ways to obtain nanoscale copper on the surface of fabrics, and chemical deposition is one of the simple and convenient methods.…”

Section: Two-dimensional (2d) Cloth Conductorsmentioning

confidence: 99%

Wearable sweat biosensors on textiles for health monitoring

Shi¹,

Zhang²,

Huang³

et al. 2023

J. Semicond.

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With the rapid technological innovation in materials engineering and device integration, a wide variety of textile-based wearable biosensors have emerged as promising platforms for personalized healthcare, exercise monitoring, and pre-diagnostics. This paper reviews the recent progress in sweat biosensors and sensing systems integrated into textiles for wearable body status monitoring. The mechanisms of biosensors that are commonly adopted for biomarkers analysis are first introduced. The classification, fabrication methods, and applications of textile conductors in different configurations and dimensions are then summarized. Afterward, innovative strategies to achieve efficient sweat collection with textile-based sensing patches are presented, followed by an in-depth discussion on nanoengineering and system integration approaches for the enhancement of sensing performance. Finally, the challenges of textile-based sweat sensing devices associated with the device reusability, washability, stability, and fabrication reproducibility are discussed from the perspective of their practical applications in wearable healthcare.

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TiO2 anchored carbon fibers as non-invasive electrochemical sensor platform for the cortisol detection

Cited by 22 publications

References 10 publications

Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring

Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring

Electrochemical Sensors for Cortisol: A Review

Wearable sweat biosensors on textiles for health monitoring

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