Topographical arrangement of hypoglossal motoneurons: An HRP study in the cat

Uemura, Masanori; Matsuda, Kiyoaki; Kume, Mamoru; Takeuchi, Yoshiki; Matsushima, Ryoka; Mizuno, Noboru

doi:10.1016/0304-3940(79)90024-7

Cited by 81 publications

(25 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ipsilateral to the injection sites, fibers appeared to terminate preferentially in several distinct regions of the hypoglossal nucleus (see Fig. 4B): (1) the ventrolateral aspect, which contains geniohyoid muscle motoneurons; (2) the dorsolateral region, which contains styloglossus and hyoglossus motoneurons; and (3) an intermediate region, which contains genioglossus motoneurons (Uemura et al 1979). By contrast, the innervation of the dorsal and ventral groups of motoneurons innervating intrinsic tongue muscles was sparse, particularly in the medial aspect of the nucleus.…”

Section: Resultsmentioning

confidence: 99%

“…These muscles are movers of the tongue: genioglossus protrudes the tongue from the mouth, hyoglossus retracts and depresses the tongue, and styloglossus draws the tongue upward and backward (Reighard and Jennings 1935). Fewer labeled terminals were noted in the vicinity of intrinsic tongue motoneurons, which produce fine movements of the tongue (Uemura et al 1979;Reighard and Jennings 1935). Other labeled projections terminated in the vicinity of geniohyoid motoneurons, which are responsible for drawing the hyoid bone forward (Reighard and Jennings 1935).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Connections of the caudal ventrolateral medullary reticular formation in the cat brainstem

Stocker¹,

Steinbacher²,

Balaban³

et al. 1997

Exp Brain Res

View full text Add to dashboard Cite

A region of the caudal ventrolateral medullary reticular formation (CVLM) participates in baroreceptor, vestibulosympathetic, and somatosympathetic reflexes; the adjacent retroambigual area is involved in generating respiratory-related activity and is essential for control of the upper airway during vocalization. However, little is known about the connections of the CVLM in the cat. In order to determine the locations of terminations of CVLM neurons, the anterograde tracers Phaseolus vulgaris leucoagglutinin and tetramethylrhodamine dextran amine were injected into this region. These injections produced a dense concentration of labeled axons throughout the lateral medullary reticular formation (lateral tegmental field), including the retrofacial nucleus and nucleus ambiguus, regions of the rostral ventrolateral medulla, the lateral and ventrolateral aspects of the hypoglossal nucleus, nucleus intercalatus, and the facial nucleus. A smaller number of labeled axons were located in the medial, lateral, and commissural subnuclei of nucleus tractus solitarius, the A5 region of the pontine reticular formation, the ventral and medial portions of the spinal and motor trigeminal nuclei, locus coeruleus, and the parabrachial nucleus. We confirmed the projection from the CVLM to both the rostral ventrolateral medulla and lateral tegmental field using retrograde tracing. Injections of biotinylated dextran amine or Fluorogold into these regions resulted in retrogradely labeled cell bodies in the CVLM. However, the neurons projecting to the lateral tegmental field were located mainly dorsal to those projecting to the rostral ventrolateral medulla, suggesting that these neurons form two groups, possibly with different inputs. Injections of retrograde tracers into the lateral tegmental field and rostral ventrolateral medulla also produced labeled cell bodies in other regions, including the medial and inferior vestibular nuclei and nucleus solitarius. These data are consistent with the view that the CVLM of the cat is a multifunctional area that regulates blood pressure, produces vocalization, affects the shape of the oral cavity, and elicits contraction of particular facial muscles.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Connections of the caudal ventrolateral medullary reticular formation in the cat brainstem

Stocker¹,

Steinbacher²,

Balaban³

et al. 1997

Exp Brain Res

View full text Add to dashboard Cite

show abstract

“…The hypoglossal complex of mammals has been described as consisting of three, four, five, and even nine subdivisions (Barnard, 1940;Lewis et al, 1971;Jansen and Korneliussen, 1977;Krammer et al, 1979;Uemura et al, 1979;Uemura-Sumi et al, 1981). However, hypoglossal motoneurons can be clustered into a ventral and a dorsal group, giving rise to the main medial and the main lateral branch of the hypoglossal nerve, respectively (Uemura- Sumi et al, 1988).…”

Section: Trigeminohypoglossal Projectionsmentioning

confidence: 96%

Trigeminal projections to hypoglossal and facial motor nuclei in the rat

Pinganaud¹,

Bernat²,

Buisseret

et al. 1999

J. Comp. Neurol.

View full text Add to dashboard Cite

“…The ventral part of the hypoglossal nucleus contains m otoneu rons innervating the geniohyoid muscle [Stuurman, 1916;Barnard, 1940;Uemura et al, 1979]. The dorsal group of NA con tains, according to Lawn [1966], Yoshidatt al.…”

Section: Autoradiographic Evidence For Afferents To Mylohyoid Geniohmentioning

confidence: 99%

Location of Motoneurons Innervating Soft Palate, Pharynx and Upper Esophagus. Anatomical Evidence for a Possible Swallowing Center in the Pontine Reticular Formation

et al. 1983

View full text Add to dashboard Cite

Retrograde HRP studies indicated that motoneurons innervating soft palate and pharynx are located in especially the dorsal group of the nucleus ambiguus, while motoneurons innervating upper esophagus and cricothyroid muscles are located in the retrofacial nucleus, the most rostral part of the nucleus ambiguus. Autoradiographic tracing techniques revealed that in the caudal pontine tegmentum an area is located just dorsal to the superior olivary complex, that projects contralaterally to the ventral part of the trigeminal motor nucleus, the dorsal group of the nucleus ambiguus and the ventral part of the hypoglossal nucleus. In these areas motoneurons are located innervating the mylohyoid, soft palate, pharynx and geniohyoid muscles respectively. Since these muscles are all involved in swallowing, a possible involvement of this pontine tegmental area in swallowing is discussed.

show abstract

Topographical arrangement of hypoglossal motoneurons: An HRP study in the cat

Cited by 81 publications

References 7 publications

Connections of the caudal ventrolateral medullary reticular formation in the cat brainstem

Connections of the caudal ventrolateral medullary reticular formation in the cat brainstem

Trigeminal projections to hypoglossal and facial motor nuclei in the rat

Location of Motoneurons Innervating Soft Palate, Pharynx and Upper Esophagus. Anatomical Evidence for a Possible Swallowing Center in the Pontine Reticular Formation

Contact Info

Product

Resources

About