Toughening of bio-ceramics scaffolds by polymer coating

Peroglio, Marianna; Grémillard, Laurent; Chevalier, Jérôme; Chazeau, Laurent; Gauthier, Catherine; Hamaide, Thierry

doi:10.1016/j.jeurceramsoc.2006.10.016

Cited by 155 publications

(114 citation statements)

References 24 publications

(19 reference statements)

Supporting

Mentioning

102

Contrasting

Order By: Relevance

“…This result can be ascribed to the formation of a uniform PDLLA/ P123 coating on the struts, as well as to the effect of polymer filling of cracks present on the surface of the struts, which will impede catastrophic crack propagation, as discussed in the literature, 32 for example, by a crack bridging mechanism. 48 The mechanical strength of the polymer coated Bioglass-based scaffolds in the present study was higher than that of similar scaffolds reported in previous studies. 21,22 This result can be due to the fact that the Bioglass-based scaffolds in the study of Li et al, 21 for example, were partially coated with polymer, while in the present work, the polymer fully covered the struts.…”

Section: Mechanical Propertiescontrasting

confidence: 74%

Development of bioactive glass based scaffolds for controlled antibiotic release in bone tissue engineering via biodegradable polymer layered coating

Nooeaid

Roether

et al. 2014

Biointerphases

View full text Add to dashboard Cite

Section: Mechanical Propertiescontrasting

confidence: 74%

Development of bioactive glass based scaffolds for controlled antibiotic release in bone tissue engineering via biodegradable polymer layered coating

Nooeaid

Roether

et al. 2014

Biointerphases

View full text Add to dashboard Cite

“…The second PCL layer was applied onto each porous structure by repeating the same procedure as described for the first layer. The resultant structure was then heated in the oven at 80 °C for 1 h to help fuse the two layers together (Peroglio et al, 2007). The uncoated, PCL single-layer coated, and PCL doublelayer coated porous structures were classified as CaSO4, PCL-CaSO4, and 2PCL-CaSO4.…”

Section: Manufacturing Processmentioning

confidence: 99%

“…Coating highly porous ceramics with PCL has been shown to augment compressive properties (Xue et al, 2009 andZhao et al, 2010). Significant improvements in toughness have also been demonstrated due to the ductile PCL fibrils bridging cracks within brittle ceramics (Peroglio et al, 2007). Due to the bioresorption and toughness, PCL has distinctly different characteristics compared to widely used 3DP ceramic materials, such as CaSO4.…”

Section: Introductionmentioning

confidence: 99%

Effects of poly (ε-caprolactone) coating on the properties of three-dimensional printed porous structures

Zhou

Cunningham

Lennon

et al. 2017

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

Powder-based inkjet three-dimensional printing (3DP) to fabricate pre-designed 3D structures has drawn increasing attention. However there are intrinsic limitations associated with 3DP technology due to the weak bonding within the printed structure, which significantly compromises its mechanical integrity. In this study, calcium sulphate ceramic structures demonstrating a porous architecture were manufactured using 3DP technology and subsequently post-processed with a poly (ε-caprolactone) (PCL) coating. PCL concentration, immersion time, and number of coating layers were the principal parameters investigated and improvement in compressive properties was the measure of success. Interparticle spacing within the 3DP structures were successfully filled with PCL material. Consequently the compressive properties, wettability, morphology, and in vitro resorption behaviour of 3DP components were significantly augmented. The average compressive strength, Young's modulus, and toughness increased 217%, 250%, and 315%, following PCL coating. Addition of a PCL surface coating provided long-term structural support to the host ceramic material, extending the resorption period from less than 7 days to a minimum of 56 days. This study has demonstrated that application of a PCL coating onto a ceramic 3DP structure was a highly effective approach to addressing some of the limitations of 3DP manufacturing and allows this advanced technology to be potentially used in a wider range of applications.

show abstract

“…Consequently, once the tensile stress is high enough to initiate a crack, the crack could rapidly propagate through the whole structure, resulting in catastrophic brittle facture. In comparison, the adherent PLA layer in the composite can provide a crack healing mechanism for the outermost glass fibers and a crack bridging mechanism for the composite structure [5][6][7][8][9][10][11][12][13][14]. Failure of the first glass fiber leads to a reduction in the load-bearing capacity of the composite and to load transfer to the neighboring fibers.…”

Section: Discussionmentioning

confidence: 99%

“…As shown for porous bioceramic scaffolds [7][8][9][10], coating the external and internal surface of porous bioactive glass scaffolds with a biodegradable polymer such as polylactic acid (PLA) or polycaprolactone (PCL) can have a strong effect on their mechanical response [6,[11][12][13]. The strength and, in particular, the work of fracture of these polymercoated bioactive glass scaffolds have shown considerable increases over the uncoated scaffolds due to crack bridging and crack healing mechanisms enabled by the polymer coating [6,11].…”

Section: Introductionmentioning

confidence: 99%

Finite Element Modeling of the Flexural Mechanical Response of Polymer-Coated Bioactive Glass Scaffolds Composed of Thermally-Bonded Unidirectional Fibers

Xiao¹,

Zaeem²,

Day³

et al. 2017

Biomedical Glasses

View full text Add to dashboard Cite

Abstract:Bioactive glasses have attractive characteristics as a scaffold material for healing bone defects but their brittle mechanical response, particularly in bending, is a concern. Recent studies have shown that coating the external surface of strong porous bioactive glass (13-93) scaffolds with an adherent biodegradable polymer layer can significantly improve their load-bearing capacity and work of fracture, resulting in a non-brittle mechanical response. In the present study, finite element modeling (FEM) was used to analyze the mechanical response in four-point bending of composites composed of a porous glass scaffold and an adherent polymer surface layer. The glass scaffold with a cylindrical geometry (diameter = 4.2 mm; porosity = 20%) was composed of randomly arranged unidirectional fibers (diameter 200-700 µm) that were bonded at their contact points. The thickness of the polymer layer was 500 µm. By analyzing the stresses in the individual glass fibers, the simulations can account for the main trends in the observed mechanical response of practical composites with a similar architecture composed of a bioactive glass (13-93) scaffold and an adherent polylactic acid surface layer. These FEM simulations could play a useful role in designing bioactive glass composites with improved mechanical properties.

show abstract

Toughening of bio-ceramics scaffolds by polymer coating

Cited by 155 publications

References 24 publications

Development of bioactive glass based scaffolds for controlled antibiotic release in bone tissue engineering via biodegradable polymer layered coating

Development of bioactive glass based scaffolds for controlled antibiotic release in bone tissue engineering via biodegradable polymer layered coating

Effects of poly (ε-caprolactone) coating on the properties of three-dimensional printed porous structures

Finite Element Modeling of the Flexural Mechanical Response of Polymer-Coated Bioactive Glass Scaffolds Composed of Thermally-Bonded Unidirectional Fibers

Contact Info

Product

Resources

About