2019
DOI: 10.1111/odi.13219
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Towards the nano‐control of periodontal inflammation?

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Cited by 5 publications
(2 citation statements)
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“…Mechanical debridement is time-consuming, expensive, and has limited therapeutic effects in sites that are difficult to reach instrumentally, such as root furcation, root concavities, and deep periodontal pockets. Additionally, systemic antimicrobial therapy not only has insufficient effective concentration in the lesion area, but it also increases the risk of microbial resistance [ 7 , 8 ]. At present, a variety of tissue engineering materials used in the treatment of periodontitis have attracted strong attention from researchers, including scaffolds [ 9 , 10 ], hydrogels [ 11 , 12 ], and nanoparticle drug delivery systems [ 13 , 14 ].…”
Section: Introductionmentioning
confidence: 99%
“…Mechanical debridement is time-consuming, expensive, and has limited therapeutic effects in sites that are difficult to reach instrumentally, such as root furcation, root concavities, and deep periodontal pockets. Additionally, systemic antimicrobial therapy not only has insufficient effective concentration in the lesion area, but it also increases the risk of microbial resistance [ 7 , 8 ]. At present, a variety of tissue engineering materials used in the treatment of periodontitis have attracted strong attention from researchers, including scaffolds [ 9 , 10 ], hydrogels [ 11 , 12 ], and nanoparticle drug delivery systems [ 13 , 14 ].…”
Section: Introductionmentioning
confidence: 99%
“…Various nanoparticulate systems have been investigated for the treatment of periodontitis [20,21]. Despite the large number of studies, there is no comprehensive and updated systematic review reporting the available evidence and/or indications for future research.…”
Section: Introductionmentioning
confidence: 99%