Towards the use of ICP-OES for the elemental analysis of organic compounds such as glucosamine

Abstract

Inductively coupled plasma optical emission spectrometry with a long demountable torch (whose outer tube is 2.5 cm longer than a standard torch) and a conventional pneumatic nebulisation system was applied to the determination of C, H and O concentrations from an organic compound dissolved in water. The sample solution was simply aspirated directly into the plasma without any sample pre-treatment (such as desolvation or degassing). The long torch was required to significantly decrease the background arising from entrained air. Good linearity was obtained for C, N, H and O upon calibration with standard solutions prepared from ultrapure tris(hydroxymethyl)aminomethane.A weighed blank correction was applied to compensate for the contribution from water, especially in the cases of H and O. Under these conditions, the detection limits for C, N, H and O were, respectively, 0.2, 50, 1000 and 2000 mmol of analyte per g of solution.Accurate concentrations, according to a Student's t test at the 95% confidence level, were measured for C, H and O in a solution of D-glucosamine hydrochloride. No internal standardisation was necessary. However, the N concentration was biased high, irrespectively of the N emission line used (from 149.262 to 593.178 nm), which rules out spectroscopic interference and will be further investigated. Nonetheless, the possibility of accurately determining C, H and O simultaneously with trace elements makes the approach quite promising. It is much simpler than alternate methods that require derivatisation of the compound prior to detection.

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“…An advanced instrument ICP-OES (Thermo Fisher Scientific, Bremen, Germany) is well-known to investigate elements of an organic compound dissolved in water. 39 The technique is commonly used to analyze the ultratrace content of an element present in solution as minor, major, and trace elements. The principle of working involves the measurement of emitted light (a completely passive process).…”

Atomic spectrometry update. Review of advances in the analysis of metals, chemicals and functional materials

“…The development of a new method for determination of C, H and O by ICP-OES in organic compounds such as glucosamine was undertaken by Odenigbo et al 91 A long demountable torch, with the outer tube being 2.5 cm longer than the regular torch, was used to reduce N emission background arising from ambient air. Operating conditions were optimized while monitoring the N 174.273 nm atomic emission line to maximize the signal-tobackground ratio.…”

A Novel Fluorescence Sensor for Iodide Detection Based on the 1,3-Diaryl Pyrazole Unit with AIE and Mechanochromic Fluorescence Behavior

“…In contrast to other halides, iodide with its large size, weaker basicity and low charge density, shows weak binding ability, which makes it a challenging task to design iodide-selective probes. For the determination of iodide, a variety of methods have been used, such as neutron activation analysis, capillary electrophoresis, iodide-selective electrodes, atomic absorption spectroscopy (AAS) [12], inductively coupled plasma mass spectrometry (ICP-MS), gas chromatography (GC) and electrostatic ion chromatography (EIC) [13][14][15][16]. Among all, ICP-MS is the most commonly used mass spectrometer.…”