Toxic metal and trace element status in the breast milk of Turkish new-born mothers

Çebi, Ayşegül; Şengül, Ümit

doi:10.1016/j.jtemb.2022.127066

Cited by 10 publications

(7 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pb concentration was also positively related to the content of Ni (r = 0.493; p = 0.0056), Cr (r = 0.468; p = 0.009), and Mn (r = 0.411; p = 0.024). Interestingly, opposite to our results, in the Turkish study 11 negative correlation between Pb and Cr was found (r = − 0.328; p < 0.05). Additionally, in the present study, Cu concentration was correlated with three other elements Cd (r = 0.478; p = 0.0076), Hg (r = 0.418; p = 0.021), and Be (r = 0.427; p = 0.037).…”

Section: Resultscontrasting

confidence: 99%

“…The levels of Pb found in our study (Table 3 ) were consistent with those reported from Slovakia (4.7 μg/L) 23 , but higher than results obtained in Turkey (2.27 ± 0.36 μg/L) 11 , Portugal (1.55 ± 1.38 μg/L) 26 , and Greece (0.48 ± 0.6 μg/L) 18 . We hypothesized that Pb present in HM originated mainly from maternal bone deposits.…”

Section: Resultssupporting

confidence: 91%

“…Considering the changes in maternal homeostasis during lactation, breastfeeding women are more susceptible to side effects from toxic elements including arsenic, cadmium, mercury, and lead 10 . It also applies to infants, mainly due to the immaturity of their gastrointestinal tract, especially the function of liver detoxification 11 . The toxic impact of heavy metals is complex and can affect the central nervous system, liver, kidneys, lungs, and immune system 5 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Essential and non-essential element concentrations in human milk samples and the assessment of infants’ exposure

Bzikowska-Jura,

Wesołowska,

Sobieraj

et al. 2024

Sci Rep

View full text Add to dashboard Cite

As the data concerning element concentrations in human milk (HM) samples and their intake by infants are lacking in Poland, the present study aimed to explore this issue. The material consisted of HM samples obtained from 30 exclusively breastfeeding mothers during 4–6 weeks postpartum. Additionally, to identify the factors that may potentially affect HM composition, information regarding maternal data (anthropometry, body composition, and diet) was also collected. Maternal diet was assessed with two methods—a food frequency questionnaire and 3-day dietary records. In total, 18 essential and non-essential elements were determined. For the elements analysis, we used inductively coupled plasma quadrupole mass spectrometry. Most of the elements (n = 11, 61%) were detected in all HM samples. In all HM samples tin concentration was higher (5.67 ± 2.39 μg/L) than the usual range reported by the World Health Organization (~ 1.0 μg/L). HM cadmium content was positively associated with maternal salty snacks intake (r = 0.502, p = 0.005), arsenic with whole-grain products intake (r = 0.37, p = 0.043), and mercury concentration with fruits and seeds/nuts consumption (r = 0.424, p = 0.042 and r = 0.378, p = 0.039, respectively). Higher HM lead concentration was predicted by maternal age (95% CI [0.94–0.97]), intake of fish (95% CI [1.01–1.03]), and vegetables (95% CI [1.02–1.06]). The highest infants’ intake was observed for copper (35.24 ± 12.48) and the lowest for arsenic (0.076 ± 0.102). Infants’ exposure to lead was associated with maternal frequency consumption of canned fish (p = 0.0045). There is a need to perform further research on this topic to maximize the benefits of breastfeeding by minimizing maternal and infant exposure to potentially toxic elements.

show abstract

Section: Resultscontrasting

confidence: 99%

Section: Resultssupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Essential and non-essential element concentrations in human milk samples and the assessment of infants’ exposure

Bzikowska-Jura,

Wesołowska,

Sobieraj

et al. 2024

Sci Rep

View full text Add to dashboard Cite

show abstract

“…In 1989 the World Health Organization and the International Atomic Energy Agency (WHO & IAEA, 1989) defined a baseline for human milk trace element concentrations still largely in use by researchers. Toxic elements in human milk may vary in concentrations depending on the level of contamination in the maternal environment, and they have been studied in developing countries associated with industrial, mining, and agricultural zones (Bansa et al, 2017; Çebi & Şengül, 2022; Mandiá et al, 2021; Motas et al, 2021; Olowoyo et al, 2021; Vahidinia et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

“…Human milk is crucial for the proper development of the new infant and is recognized as the gold standard for infant nutrition. Some toxic trace elements can enter human milk through food consumption, drinking water, air, or incidental soil ingestion, and are of concern to the nursing infant (Çebi & Şengül, 2022; Olowoyo et al, 2021). Toxic elements can be transferred to milk through maternal blood, even at relatively low concentrations.…”

Section: Introductionmentioning

confidence: 99%

Concentrations of Lead and Arsenic in Mother’s Milk and Children’s Blood in Peruvian Breastfeeding Dyads

Linares,

Thaxton-Wiggins,

Unrine

2023

J Hum Lact

View full text Add to dashboard Cite

Background: Toxic trace elements could enter human milk through mothers’ food consumption, drinking water, air, or incidental soil ingestion, and are of concern to the nursing infant. Research Aim: To determine the concentration of toxic trace elements (lead and arsenic) in Peruvian mothers’ milk and their association with blood concentrations in their own infants 3–20 months old. Method: This exploratory, cross-sectional study, carried out in Peru, included breastfeeding mother/child dyads ( N = 40). Following standardized protocols, biospecimens of human milk and child’s blood were collected. Results: Lead and arsenic concentrations in milk were above the method detection limits in 73% and 100% of samples with median concentrations of 0.26 µg/L ( IQR = 0.10, 0.33 µg/L) and 0.73 µg/L ( IQR = 0.63, 0.91 µg/L), respectively. Concentrations of lead and arsenic in blood were 2.05 µg/dL ( SD = 1.35), and 1.43 µg/dl (geometric mean: SD = 1.39), respectively. Blood lead concentrations in 12.5% ( n = 5) of the samples were above the U.S. Center for Disease Control and Prevention reference value (< 3.5 µg/dl), and over half of arsenic concentrations were above the acceptable levels of < 1.3 µg/dl (Mayo Clinic Interpretative Handbook). Our results showed that for every one-month increase in age, lead blood concentrations increased by 0.1 µg/dl ( p = 0.023). Additionally, every 1 µg/L increase in the mother’s milk arsenic was associated with a 1.40 µg/dl increase in the child’s blood arsenic concentration. Conclusions: Implementing effective interventions to decrease the toxic exposure of reproductive-aged women is needed in Peru and worldwide.

show abstract

Lactational Exposure of Human Infants to Metal (loid)s: A Comparison of Industrial and Urban Inhabitants in North of the Persian Gulf

Amiri,

Khalili Doroodzani,

Ostovar

et al. 2023

Biol Trace Elem Res

View full text Add to dashboard Cite

In this study, postnatal metal (loid)s (MLs) exposure was compared between the petrochemical and gas area of Asaluyeh (PGA) and urban area of Kaki (UA) in Bushehr province, Iran. Two hundred human breast milk (BM) samples from the industrial and urban areas were analyzed for MLs using Inductivity Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Boron (B), cooper (Cu), iron (Fe), and nickel (Ni) were found at the highest levels in both study areas. Adjusted multiple linear regression models revealed that the mean concentration of total MLs in BM samples collected from the PGA was statistically signi cantly greater than that of the UA (655.85 vs. 338.17 µg/L). Also, the mean concentrations of all detected MLs in BM samples collected from the PGA were statistically signi cantly higher than those collected from the UA. The hazard index (HI) of combined MLs in the PGA and UA illustrated non-cancer risk for infants. Lead (Pb) and chromium (Cr) in the PGA and Cr in the UA showed the risk of cancer. So it can be concluded that nursing infants from an industrial area are most at risk for MLs exposure during entire lactation course than those from an urban area.

show abstract

Toxic metal and trace element status in the breast milk of Turkish new-born mothers

Cited by 10 publications

References 40 publications

Essential and non-essential element concentrations in human milk samples and the assessment of infants’ exposure

Essential and non-essential element concentrations in human milk samples and the assessment of infants’ exposure

Concentrations of Lead and Arsenic in Mother’s Milk and Children’s Blood in Peruvian Breastfeeding Dyads

Lactational Exposure of Human Infants to Metal (loid)s: A Comparison of Industrial and Urban Inhabitants in North of the Persian Gulf

Contact Info

Product

Resources

About