Toxicity of Ag Nanoparticles Synthesized Using Stearic Acid from Catharanthus roseus Leaf Extract Against Earias vittella and Mosquito Vectors (Culex quinquefasciatus and Aedes aegypti)

Pavunraj, Manickam; Baskar, Kathirvelu; Duraipandiyan, Veeramuthu; Al-Dhabi, Naïf Abdullah; Rajendran, V.; Benelli, Giovanni

doi:10.1007/s10876-017-1235-8

Cited by 27 publications

(11 citation statements)

References 58 publications

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“…When evaluated at 200 ppm, the nanoparticles demonstrated strong antifeedant (87.13 percent) and larvicidal (93.77 percent) activity against E. vittella, with LC50 values of 45.46 ppm in antifeedant studies and 25.12 ppm in larvicidal assays. The nanoparticles were found to have acute toxicity against the mosquitoes Culex quinquefasciatus and Aedes aegypti, with LC50 values of less than 40 ppm in both vectors, indicating their potential for developing novel and more effective biopesticides to combat arthropod pests 29 .…”

Section: Anti-malarial Activitymentioning

confidence: 99%

To Review on the Pharmacology of the Leaf Extract of Catharanthus Roseus

Parihar

Sharma

Chirania³

et al. 2022

Asian J Pharm Res Dev

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Catharanthus roseus a species, a well-known home-grown herb in India, that belong to the genus Catharanthus of the Apocynaceae family. The Catharanthus roseusroots, stems, flowers and leaves are employed in herbal therapy, and also used as a herbal plant and ornamental plant. It is native and endemic to Madagascar, although it is also planted as an ornamental and therapeutic plant in other parts of the world. Pharmacological and therapeutic research, on the leaf of the Catharanthus roseusand its active components are presented in this overview.

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Section: Anti-malarial Activitymentioning

confidence: 99%

To Review on the Pharmacology of the Leaf Extract of Catharanthus Roseus

Parihar

Sharma

Chirania³

et al. 2022

Asian J Pharm Res Dev

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“…aegypti that can spread dengue virus and Culex quinquefasciatus or An. stephensi that transmit Zika virus were presented in several papers (e.g., Jampílek and Kráľová 2019d;Govindarajan and Benelli 2017;Lallawmawma et al 2015;Pavunraj et al 2017;Ishwarya et al 2017;Suganya et al 2017).…”

Section: Dengue Virus and Zika Virusmentioning

confidence: 99%

Nanoformulations: A Valuable Tool in the Therapy of Viral Diseases Attacking Humans and Animals

Jampílek

Kráľová

2019

Nanotheranostics

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Various viruses can be considered as one of the most frequent causes of human diseases, from mild illnesses to really serious sicknesses that end fatally. Numerous viruses are also pathogenic to animals and plants, and many of them, mutating, become pathogenic also to humans. Several cases of affecting humans by originally animal viruses have been confirmed. Viral infections cause significant morbidity and mortality in humans, the increase of which is caused by general immunosuppression of the world population, changes in climate, and overall globalization. In spite of the fact that the pharmaceutical industry pays great attention to human viral infections, many of clinically used antivirals demonstrate also increased toxicity against human cells, limited bioavailability, and thus, not entirely suitable therapeutic profile. In addition, due to resistance, a combination of antivirals is needed for life-threatening infections. Thus, the development of new antiviral agents is of great importance for the control of virus spread. On the other hand, the discovery and development of structurally new antivirals represent risks. Therefore, another strategy is being developed, namely the reformulation of existing antivirals into nanoformulations and investigation of various metal and metalloid nanoparticles with respect to their diagnostic, prophylactic, and therapeutic antiviral applications. This chapter is focused on nanoscale materials/formulations with the potential to be used for the treatment or inhibition of the spread of viral diseases caused by human immunodeficiency virus, influenza A viruses (subtypes H3N2 and H1N1), avian influenza and swine influenza viruses, respiratory syncytial virus, herpes simplex virus, hepatitis B and C viruses, Ebola and Marburg viruses, Newcastle disease virus, dengue and Zika viruses, and pseudorabies virus. Effective antiviral long-lasting and target-selective nanoformulations developed for oral, intravenous, intramuscular, intranasal, intrarectal, intravaginal, and intradermal applications are discussed.

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“…Catharanthus roseus displays as the anticancer or anti-carcinogenic agents (van Der Heijden et al 2004;Mustafa and Verpoorte 2006;Leveque and Jehl 2007;Ferreres and Pereira 2008;Shukla and Khanuja 2013;Qu et al 2018) and antioxidant agents (Jaleel et al 2006a(Jaleel et al , 2006b. Too the ornamented regard, the C. roseus plant is perceived to have different pharmacological exercises of medical importance for example, mitigating, cancer prevention agent and anticarcinogenic properties (van Der Heijden et al 2004;Chen et al 2017); antibacterial activity (Govindasamy and Srinivasan 2012;Syeda and Riazunnisa 2020); antimitotic activity (Alam et al 2017); antitumor activity (Wang et al 2016a(Wang et al , 2016b; antidiabetic activity (Yao et al 2013;Goboza et al 2020); antifeedant and larvicidal activities against Earias vittella, larvicidal on Culex quinquefasciatus (house mosquito) and Aedes aegypti (yellow fever mosquito) (Pavunraj et al 2016(Pavunraj et al , 2017. Various pieces of the plant structure an expected spice to x different diseases and issues, for example, therapy of a few sicknesses like diabetes, jungle fever and Hodgkin's lymphoma (Alam et al 2017;Kaur et al 2017), to control drain and scurvy, as a mouthwash for toothache, and for the recuperating and cleaning of persistent injuries, to treat diabetic ulcer and oral hypoglycemic specialist (Aruna et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Biological Isolation and Characterization of Catharanthus roseus (L.) G. Don Methanolic Leaf Extracts and their Assessment of Antimicrobial, Cytotoxic and Apoptotic Activities

Rajashekara

Reena

Mainavi

et al. 2022

Preprint

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Background: Biological synthesis of natural products from the plants has made us an inspiring methodology in the arena of science and biotechnology. Methods: The methanolic leaf extracts of Catharanthus roseus (L.) G. Don plants (CrPLE) were isolated/extracted and characterized utilizing phytochemicals estimation, Thin-layer chromatography (TLC) and High-Performance Liquid Chromatography (HPLC) analysis; and further in understanding the biomedical uses of CrPLE. The evaluation of the seven phytochemicals clearly designates that the presence of secondary metabolites in the CrPLE. Results: The CrPLE (test samples) exhibited the Catechin and Caffeic acid contents of 0.0055 and 0.0149 mg/g respectively. The CrPLE unveiled highest antimicrobial activity and confirmed with mortal effect against the tested microorganisms. A cytotoxicity known against the breast cancer cell lines of exposed that CrPLE as a good anticancer agent and metabolically vigorous cells. Conclusion: Consequently, the biological synthesized methanolic leaf extracts of the C. roseus plants would be appreciated and have the incredible contributions in the field of medicinal applications.

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Toxicity of Ag Nanoparticles Synthesized Using Stearic Acid from Catharanthus roseus Leaf Extract Against Earias vittella and Mosquito Vectors (Culex quinquefasciatus and Aedes aegypti)

Cited by 27 publications

References 58 publications

To Review on the Pharmacology of the Leaf Extract of Catharanthus Roseus

To Review on the Pharmacology of the Leaf Extract of Catharanthus Roseus

Nanoformulations: A Valuable Tool in the Therapy of Viral Diseases Attacking Humans and Animals

Biological Isolation and Characterization of Catharanthus roseus (L.) G. Don Methanolic Leaf Extracts and their Assessment of Antimicrobial, Cytotoxic and Apoptotic Activities

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