Toxicological Effects of Lead and Zinc on the Antioxidant Enzyme Activities of Post Juvenile Clarias gariepinus

Saliu, Joseph Kayode; Bawa-Allah, Kafilat A.

doi:10.5923/j.re.20120201.03

Cited by 48 publications

(37 citation statements)

References 9 publications

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“…In line to this finding, African catfish Clarias graiepinus showed decreased levels of GSH after exposure to 100 μg/l, 300 μg/l and 500 μg/l of lead nitrate (Osman et al, 2007). In another study, GSH level was reduced after 28 days exposure to 5.15, 0.52, 0.052 mg/L of Pb(NO 3 ) 2 compared to the controls (Saliu and Bawa-Allah, 2012). The decreased GSH levels in the present study could account for the marked lipid peroxidation tables (1).…”

Section: Resultsmentioning

confidence: 53%

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Effects of lead on some oxidative stress of the African catfish, Clarias gariepinus

Elarabany

Alfakheri

Bahnasawy

2018

Journal of Egyptian Academic Society for Environmental Developm

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This study aimed to determine the effects of sub-lethal concentrations of lead (PbCl2) on some oxidative stress in the African catfish Clarias gariepinus. Fishes were captured from Manzala Lake, Egypt. They were acclimatized and fed with commercial fish diet for one month before starting the experiment. Two experimental groups were exposed to two sublethal concentrations (10% and 30% of LC 50 ) of lead chloride, fishes from different experimental groups were sacrificed after 60 days of exposure. Oxidative stress enzymes such as GSH, CAT, SOD, and MDA were estimated. Group treated with Pb10 % showed significantly lower concentrations of GSH. On the other hand, Pb 30% group showed a significantly higher concentration of CAT, MDA and SOD.

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Section: Resultsmentioning

confidence: 53%

“…Studies on the effect of lead on C. gariepinus showed that it caused a reduction in oxidative stress and CAT was significantly higher compared to the control group (Loveline et al, 2018). Exposure of the African catfish C.gariepinus to Pb (NO 3 ) 2 caused reduction in GSH, SOD, CAT and MDA compared to control (Saliu and Bawa-Allah, 2012).…”

Section: Introductionmentioning

confidence: 86%

Effects of lead on some oxidative stress of the African catfish, Clarias gariepinus

Elarabany

Alfakheri

Bahnasawy

2018

Journal of Egyptian Academic Society for Environmental Developm

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“…Malondialdehyde (MDA) is one of the oxidative damage products of lipid peroxidation. Its presence in tissues indicates oxidative stress [64]. A decrease in the activities of these antioxidant enzymes can lead to an excess availability of O2 and H 2 O 2 , which in turn generate OH, resulting in initiation and propagation of lipid peroxydation [65].…”

Section: Discussionmentioning

confidence: 99%

Neuroprotective and Antiamnesic Effects ofMitragyna inermisWilld (Rubiaceae) on Scopolamine-Induced Memory Impairment in Mice

Pahaye

Bum

Taïwé

et al. 2017

Behavioural Neurology

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Aim. To assess memory improvement and neuroprotective and antioxidant effects of Mitragyna inermis (M. inermis) leaf decoction on the central nervous system. Methodology. Leaf decoction of M. inermis was tested on learning and memory in normal and scopolamine-induced cognitive impairment in mice using memory behavioral tests such as the Morris water maze, object recognition task, and elevated plus maze. Oxidative stress enzymes—catalase, superoxide dismutase, and the thiobarbituric acid reactive substance, a product of lipid peroxidation—were quantified. In each test, mice 18 to 25 g were divided into groups of 5. Results. The extract reversed the effects of scopolamine in mice. The extract significantly increased discrimination index in the object recognition task test and inflexion ratio in the elevated plus maze test. The times spent in target quadrant in MWM increased while the transfer latency decreased in mice treated by M. inermis at the dose of 196.5 mg/kg. The activity levels of superoxide dismutase and catalase were significantly increased, whereas the thiobarbituric acid reactive substance was significantly decreased after 8 consecutive days of treatment with M. inermis at the dose of 393 mg/kg. Conclusion. These results suggest that M. inermis leaf extract possess potential antiamnesic effects.

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“…Animal experiment: Male albino rats (25) with mean weight 95 ± 5.32 g and mean age 3-4 weeks were divided into three groups BRC CB and HNB and housed in rat cages. They were allowed access to water and feed diet ad libitum for them to acclimatize to laboratory conditions.…”

Section: Introductionmentioning

confidence: 99%

Nutritional Properties and Toxicological Assessment of High Nutrient Biscuit Developed from Blends of Some Cereals and Legume

OB¹,

GN²

2015

J Nutr Disorders Ther

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Materials and Methods Materials Soybean, sorghum, maize, wheatflour, sugar, salt, fat, Sodium bicarbonate (baking powder), lecithin and milk were purchased from the main market in Mushin Lagos State Nigeria. Methods Production of biscuit: Biscuits were produced at laboratory scale using the method of Ayo [10] with a slight modification. Determination of nutritional composition: Nutrition composition of the biscuit was determined using established methods. Proximate and mineral composition was determined using the method of AOAC [11]. Vitamin analysis was also carried via high performance liquid chromatography (HPLC) using the method of AOAC [11]. Sensory evaluation: Sensory evaluation was conducted on the developed biscuit at laboratory scale according to the method described [12]. It was compared to readily available commercial biscuit. They were given the reference codes HNB and CB for the developed and

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Toxicological Effects of Lead and Zinc on the Antioxidant Enzyme Activities of Post Juvenile Clarias gariepinus

Cited by 48 publications

References 9 publications

Effects of lead on some oxidative stress of the African catfish, Clarias gariepinus

Effects of lead on some oxidative stress of the African catfish, Clarias gariepinus

Neuroprotective and Antiamnesic Effects ofMitragyna inermisWilld (Rubiaceae) on Scopolamine-Induced Memory Impairment in Mice

Nutritional Properties and Toxicological Assessment of High Nutrient Biscuit Developed from Blends of Some Cereals and Legume

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