Trace Elements in Human Tissue Part III. Subjects from Africa, the Near and Far East and Europe

Tipton, Isabel H.; Schroeder, Hannes; Perry, Horace M.; Cook, M. J.

doi:10.1097/00004032-196505000-00006

Cited by 136 publications

(17 citation statements)

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“…Most authors have taken samples for analysis from subjects who have died abruptly in accidents, but they hav,e also included subjects with 'known diseases (1,9,25). Even subjects with dissimilar diseases have been used as control groups in studies concerning tissue copper concentrations in certain other diseases (11,14,15).…”

Section: Resultsmentioning

confidence: 99%

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Biologically active metals in human tissues. I. The effect of age and sex on the concentration of copper in aorta, heart, kidney, liver, lung, pancreas and skeletal muscle.

Vuori¹,

Huunan-Seppälä²,

Kilpiö³

1978

Scand J Work Environ Health

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Biologically active metals in human tissues. I. The effect of age and sex on the concentration of copper in aorta, heart, kidney, liver, lung, pancreas and skeletal muscle.by Vuori E, Huunan-Seppälä A, Kilpiö JO 4 (1978) 167-175. Autopsy specimens of aorta, heart, kidney, liver, lung, pancreas and skeletal muscle were collected from 86 accident victims. The ,capper concentration~n each tissue was determined w1th aJtomic absorption spectrophotometry. The descending order of the tissues in respect to capper COThcenltrartJiJon was: liver, heart, kidn'ey, pan-cr,eas, lung, muscle, and aorta. No signdfioaoIlJt difference was found in 1Jhe oopper leV€lls of samples from male and female autopsies. When the effect of age on the averag,e copper concentration was studied, liver and kidney showed oa decreaffiJng concentrntiQn .up to matumy, the copper oonoenltratdon in pancreas and s'keIetal muscle showed a

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Section: Resultsmentioning

confidence: 99%

“…Besides, some materilals comprise not only healthy persons who had died :in .aocidents, but also chronically ill, hospitalized patients (1,7,9,11,14,16,25).…”

Section: Resultsmentioning

confidence: 99%

Biologically active metals in human tissues. I. The effect of age and sex on the concentration of copper in aorta, heart, kidney, liver, lung, pancreas and skeletal muscle.

Vuori¹,

Huunan-Seppälä²,

Kilpiö³

1978

Scand J Work Environ Health

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“…Table 10 gives the data obtained by Tipton et al'. (299) which were specifically intended to show geographic variations in Al concentration in tissues obtained from adult males who had lived in four geographic locations.…”

Section: Tolerances (Or Maximum Allowable Concentrations) In Foods Anmentioning

confidence: 99%

“…Nerve Tissue: In addition to adult brain data provided by Tipton (297,299) (Tables 7, 9, and 10) and others (432)(433)(434)(435)(436)(437)(438) (308). These data offer evidence that Al may be essential with regard to brain tissue development and activity.…”

Section: August 1974mentioning

confidence: 99%

Aluminum in the Environment and Human Health

Sorenson¹,

Campbell²,

Tepper³

et al. 1974

Environmental Health Perspectives

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The review of over 800 references on aluminum (Al) published since the mid-fifties covers the occurrence of Al in soil, air, water, plants and food products, as well as air and water pollution problems. In addition, the existing quality criteria, the biology and toxicology of Al, and the therapeutic and medical uses are presented. It is concluded that absorption and retention or accumulation of Al in humans occurs at lower levels of intake than had been assumed formerly. However, levels of 5 to 50 times the normal daily intake do not appear to interfere with other metabolic processes. The adverse effects of Al reported in the more recent years resulted from the inhalation or ingestion of Al in concentrations many times greater than the amounts present under normal circumstances. As in the past, there is still no need for .ncern by the public or producers of Al or its products concerning hazards to human health derived from well established and extensively used products.

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“…This element is essential for various cellular activities such as cell division, DNA replication, and RNA and protein synthesis [16,17]. Zinc can be detected in numerous organs, including the liver, cerebral cortex, prostate, bone, kidney, muscle, and pancreas [18,19] . In the exocrine pancreas, zinc is concentrated by the acinar cells and is secreted into the duodenum in the pancreatic juice [20,21].…”

Section: Discussionmentioning

confidence: 99%

Effect of Zinc on Experimental Acute Pancreatitis in Rats.

Takeda

Yoshikawa

Morita

et al. 1999

J. Clin. Biochem. Nutr.

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SummaryThe effects of zinc on acute pancreatitis were investigated in rats with cerulein-induced pancreatitis and taurocholate+trypsin-induced pancreatitis. The endogenous zinc concentrations in the serum and pancreas after the onset of acute pancreatitis was not different from those in normal rats. Orally administered zinc sulfate was well absorbed and was taken up by the pancreas in normal rats as well as in rats suffering from acute pancreatitis.Oral administration of zinc sulfate before induction of acute pancreatitis reduced the serum amylase activity and the wet weight of the pancreas in rats treated with cerulein or taurocholate+trypsin.Oral administration of zinc sulfate after the induction of acute pancreatitis also reduced the pancreatic wet weight in rats with cerulein-induced pancreatitis, and decreased the mortality rate in rats with taurocholate + trypsin-induced pancreatitis.N-(3-aminopropionyl)-L-histidinato zinc (polaprezinc), a chelate of zinc and L-carnosine, also decreased the serum amylase activity and pancreatic wet weight in both types of pancreatitis. These data suggest that zinc compounds may have a therapeutic effect on acute pancreatitis. Zinc is an essential trace element for many biological processes in humans and animals. It has various regulatory functions such as inhibition of platelet aggregation and serotonin release [1], inhibition of histamine release from mast cells [2], inhibition of migration and phagocytosis by macrophages and polymorphonuclear leukocytes [3], and inhibition of granulocyte oxygen consumption and bactericidal activity against Escherichia coil [4]. Moreover, zinc may also function as

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Trace Elements in Human Tissue Part III. Subjects from Africa, the Near and Far East and Europe

Cited by 136 publications

References 0 publications

Biologically active metals in human tissues. I. The effect of age and sex on the concentration of copper in aorta, heart, kidney, liver, lung, pancreas and skeletal muscle.

Biologically active metals in human tissues. I. The effect of age and sex on the concentration of copper in aorta, heart, kidney, liver, lung, pancreas and skeletal muscle.

Aluminum in the Environment and Human Health

Effect of Zinc on Experimental Acute Pancreatitis in Rats.

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