Trace Elements (Zn and Cu) and Oxidative Stress in Pediatric Patients with Persistent Allergic Rhinitis

Gunizi, Huseyin; Savaş, Hasan Basri; Genc, Sibel Kuloglu

doi:10.29271/jcpsp.2022.03.324

Cited by 4 publications

(1 citation statement)

References 1 publication

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“…In various studies conducted in adult and pediatric age groups, AR patients and healthy control groups were compared and it was shown that serum Zn was significantly lower in the AR patient group (16)(17)(18). Conversely, there are also works demonstrations that there is no significant distinction (15).…”

Section: Discussionmentioning

confidence: 99%

Analysis of the Relationship Between Serum Zinc Values and Allergic Rhinitis Parameters in Patients with Allergic Rhinitis

KUBAT¹,

SARIOĞLU²

2023

tjhealthsport

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Background/Aim: Zinc is an significant trace element that acts an active part in the immune system and is associated with allergic inflammatory diseases. In the literature, various results have been shown in studies on the coexistence of serum zinc level and allergic rhinitis. The objective of this research was to analyze the intercourse among serum zinc levels and whole blood parameters in allergic rhinitis (AR). Method:In this research, patients were appraised in consistency with the instruction for "Allergic Rhinitis and Its Effect on Asthma". Serum total Ig E, C-reactive protein grades in the AR group and leukocyte, neutrophil, eosinophil and lymphocyte counts, neutrophil/lymphocyte, eosinophil/lymphocyte, platelet/lymphocyte ratio and serum zinc values in whole-blood parameters of all cases were analyzed and contrasted between the AR and control groups.Findings: Neutrophil and eosinophil counts and eosinophil/lymphocyte ratio were presented as significantly superior in the AR category than in the control category (p<0.05). Serum zinc values in the AR category were remarkably underneath than those in the control category (p<0.05). In the univariate model, it was noticed that the eosinophil and zinc values had a significant-independent differential effect in distinguishing the AR and control category patients (p< 0.05). Conclusion:Serum zinc level, neutrophil and eosinophil count, eosinophil/lymphocyte ratio in the blood are practical biochemical indicators that can be used to recognition, treatment, together with following-up of cases with allergic rhinitis. It is assumed that with the support of zinc deficiency, important clinical benefits can be achieved in anti-allergic treatment.

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Section: Discussionmentioning

confidence: 99%

Analysis of the Relationship Between Serum Zinc Values and Allergic Rhinitis Parameters in Patients with Allergic Rhinitis

KUBAT¹,

SARIOĞLU²

2023

tjhealthsport

View full text Add to dashboard Cite

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Effects of micronutrients and macronutrients on risk of allergic disease in the European population: a Mendelian randomization study

Zeng,

Wu,

Pan

et al. 2024

Food and Agricultural Immunology

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The Role of Selected Trace Elements in Oxidoreductive Homeostasis in Patients with Thyroid Diseases

Wróblewski

Wróblewska

Nuszkiewicz

et al. 2023

IJMS

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Impaired levels of selenium (Se), zinc (Zn), copper (Cu), iron (Fe), manganese (Mn) and iodine (I) in the organism may adversely affect the thyroid endocrine system. These trace elements play a role in the fight against oxidative stress as components of enzymes. Oxidative–antioxidant imbalance is considered a possible factor in many pathological conditions, including various thyroid diseases. In the available literature, there are few scientific studies showing a direct correlation of the effect of supplementation of trace elements on slowing down or preventing the occurrence of thyroid diseases in combination with the improvement of the antioxidant profile, or through the action of these elements as antioxidants. Among the available studies, it has been shown that an increase in lipid peroxidation levels and a decrease in the overall antioxidant defense status occur during such thyroid diseases as thyroid cancer, Hashimoto’s thyroiditis and dysthyroidism. In studies in which trace elements were supplemented, the following were observed: a decrease in the level of malondialdehyde after supplementation with Zn during hypothyroidism and reduction in the malondialdehyde level after Se supplementation with a simultaneous increase in the total activity status and activity of antioxidant defense enzymes in the course of autoimmune thyroiditis. This systematic review aimed to present the current state of knowledge about the relationship between trace elements and thyroid diseases in terms of oxidoreductive homeostasis.

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Trace Elements (Zn and Cu) and Oxidative Stress in Pediatric Patients with Persistent Allergic Rhinitis

Abstract: Objective: To investigate the relationship between complaints and serum trace elements and oxidative stress levels in pediatric patients with allergic rhinitis (AR).

Cited by 4 publications

References 1 publication

Analysis of the Relationship Between Serum Zinc Values and Allergic Rhinitis Parameters in Patients with Allergic Rhinitis

Analysis of the Relationship Between Serum Zinc Values and Allergic Rhinitis Parameters in Patients with Allergic Rhinitis

Effects of micronutrients and macronutrients on risk of allergic disease in the European population: a Mendelian randomization study

The Role of Selected Trace Elements in Oxidoreductive Homeostasis in Patients with Thyroid Diseases

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