Traitement des cancers volumineux du col utérin de stades I et II

Ferrer, Catherine; Panel, Laure; Dupaigne, D; Bons, F.; Debrigode, C.; Marès, P.; Tayrac, Renaud de

doi:10.1016/s0246-1064(07)45873-x

Cited by 3 publications

(5 citation statements)

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“…Therapeutic option for maintaining pregnancy Neoadjuvant chemotherapy in advanced cervical cancer causes the regression of tumor size and is considered a promising technique in curative management [34]. But, the use of this technique during pregnancy is controversial since its impact on growth and fetal health is poorly understood and potentially dangerous.…”

Section: Management Of Cervical Cancermentioning

confidence: 99%

Management of Pregnant Women with Invasive Cervical Cancer about Ten Cases

Diabaté¹,

Bakkali²,

Lachgar³

et al. 2018

JCT

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The purpose of this study was to update the management of invasive cervical cancers diagnosed during pregnancy. Patients and methods: This study was performed retrospectively at radiotherapy department of National Institute of Oncology Rabat Morocco. From 01/04/2005 to 31/05/2010, ten patients with invasive cervical cancer during pregnancy were included. Results: Ten patients were included in the study. The staging was as follow: stage IIIB (n = 4); stage IIB (n = 2) and stage IB2 (n = 4). The radical abdominal hysterectomy with pelvic lymphadenectomy was performed in five patients; a therapeutic interruption of pregnancy was performed in four patients. One pregnancy has resulted in the birth of a living child (by cesarean section). Adjuvant treatment was concomitant chemoradiotherapy followed by low dose rate (LDR) brachytherapy in three patients; adjuvant concomitant chemoradiotherapy followed by high dose rate (HDR) brachytherapy was performed in four patients; a HDR brachytherapy was done in one patient. Two patients have received an exclusive external radiotherapy. After a median follow-up of 4 years (2 -7 years), there were bone and lung metastases in one patient. Nine patients are alive after completed treatment. Conclusion: Our series focused on ten patients with invasive cervical cancer during pregnancy. Management is complex and requires discussion in a multidisciplinary meeting. Routine screening of cervical cancer and awareness are the key point to improve the treatment and survival rate of patients. The management of all cases is according to international recommendations.

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Section: Management Of Cervical Cancermentioning

confidence: 99%

Management of Pregnant Women with Invasive Cervical Cancer about Ten Cases

Diabaté¹,

Bakkali²,

Lachgar³

et al. 2018

JCT

View full text Add to dashboard Cite

show abstract

“…Selon l'Encyclopédie Médico-Chirurgicale et la méta-analyse de Green, le traitement des stades avancés et des tumeurs volumineuses fait appel à la radiothérapie plus ou moins associée à la chirurgie ou à la chimiothérapie [39][40][41].…”

Section: Traitementunclassified

“…La chimiothérapie néoadjuvante dans les cancers avancés du col entraîne une régression de la taille tumorale et est considérée comme une technique prometteuse dans la prise en charge curative [39].…”

Section: Chimiothérapie Néoadjuvanteunclassified

“…En effet, cinq essais réalisés chez des patientes en dehors de la grossesse ont démontré le bénéfice de l'association radiochimiothérapique utilisant du cisplatine avec une amé-lioration de la survie globale de 12 % selon la méta-analyse de Green [39][40][41].…”

Section: Radiochimiothérapie Concomittanteunclassified

“…Un geste chirurgical complémentaire, associant une hystérectomie et une lymphadénectomie, semble apporter un bénéfice pour les volumineux cancers du col utérin ne dépassant pas 6 cm et lorsque l'on suspecte l'existence d'un résidu tumoral après radiochimiothérapie [39].…”

Section: Radiochimiothérapie Concomittanteunclassified

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