Trajectories of length, weight, and bone mineral density among preterm infants during the first 12 months of corrected age in China

Abstract

BackgroundLimited evidence has been provided on the trajectories of length, weight, and bone mineral density (BMD) among preterm infants in early life in Asian countries.MethodsWe conducted a longitudinal study, which included 652 late preterm (gestational age: 34–36.9 weeks), 486 moderate preterm (32–33.9), 291 very preterm (28–31.9), 149 extremely preterm infants (≤28.9) and 1434 full-term peers (≥37) during the first 12 months of corrected age in Wuhan, China. Weight and length were measured at birth, once randomly before term, and every month thereafter. BMD was examined at 3, 6, 9 and 12 months using dual-energy X-ray absorptiometry.ResultsFrom birth to 12 months of corrected age, growth peaks in length and weight were observed at 1–3 months among preterm infants. No catch-up growth in length, weight, and BMD was observed among preterm infants. However, accelerated growth in length, weight, and BMD was found. Among extremely preterm infants, relative to full-term infants, length was −6.77 cm (95 % CI: −7.14, −6.40; P for trend < 0.001) lower during the first 12 months; weight was −1.23 kg (−1.33, −1.13; P for trend < 0.001) lower; and BMD was −0.070 g/cm2(−0.087, −0.053; P for trend < 0.001) lower; however, average growth rates of these measures were higher (Ps < 0.05). Small gestational age and low birth weight were independently associated with lower length, weight, and BMD.ConclusionGrowth peaks in length and weight among preterm infants were observed at 1–3 months. No catch-up growth in length, weight, and BMD was observed, however, there was accelerated growth in length, weight, and BMD.Electronic supplementary materialThe online version of this article (doi:10.1186/s12887-015-0396-6) contains supplementary material, which is available to authorized users.

Postnatal growth in preterm infants during the first year of life: A population-based cohort study in China

“…The weight and length of both males and females in preterm infants did not achieve the median measurements of their term peers. Zhao et al [20] found a faster growth rate in preterm infants during the first 12 months of age with the growth rate peaking at 1–3 months of age, but not yet catch up with term infants. Another study from China reported the catch-up growth occurred from 10th and 12th month for weight and length, respectively [21].…”

First-year growth of 834 preterm infants in a Chinese population: a single-center study

“…The catch-up growth patterns of preterm infants have been a matter of debate. Zhao et al [4] observed no catch-up growth in weight and length among preterm infants, while Westerberg et al [5] observed that VLBW infants showed significant catch-up growth in both weight and length during the first year of life. Thus, an understanding of the early growth patterns of preterm infants is important and may help improve appropriate daily care practices and reduce the morbidity of growth deviations related to preterm birth.…”

Avaliação Do Estado Nutricional De Recém-Nascidos Pré-Termo Em Unidade De Terapia Intensiva Neonatal / Assessment of Nutritional Status of Preterm Newborns in the Neonatal Intensive Care Unit

“…Por fim, a fase de equilíbrio, caracteriza-se por uma velocidade de crescimento comparável à das crianças saudáveis nascidas a termo (CARDOSO-DEMARTINI; BAGATIN; SILVA; BOGUSZEWSKI, 2011). Cabe destacar que, a intensidade e duração destas fases variam de acordo com a idade gestacional, o peso de nascimento e a gravidade da condição do RN (BOCCA-TJEERTES;VAN BUUREN;BOS;KERSTJENS et al, 2012;LIU;LUO;PENG;XIONG et al, 2019;ZHAO;DING;HU;DAI et al, 2015).Alguns fatores podem influenciar o crescimento pós-natal de prematuros, tais como as intercorrências durante o período de internação e pós-alta hospitalar (ROVER; VIERA; SILVEIRA; GUIMARÃES et al, 2016), as práticas alimentares pós-natais (DAMASCENO; SILVA; XIMENES NETO; FERREIRA et al, 2014) e o estado nutricional ao nascimento (LIMA; CARVALHO; COSTA; MOREIRA, 2014). Durante o perído de internação os principais fatores associados à danos no crescimento do prematuro são as intercorrências clínicas, como infecções, distúbios do trato gastrointestinal e impossibilidade de ingestão alimentar adequada (ALTERMAN, 2016).…”