“…Burton et al, 1988;Colinet et al, 2010;Stetina et al, 2015;Tungjitwitayakul et al, 2015). Recently, however, various authors have begun to show that chaperones contribute to the natural winter diapause and/or cold hardiness of insects (Sonoda et al, 2006;Kayukawa et al, 2005;Chen et al, 2006;Kayukawa and Ishikawa, 2009;Rinehart et al, 2006Rinehart et al, , 2007Yu et al, 2016); for review also see Storey and Storey (2011) and King and MacRae (2015). Indeed, work by our group has shown that larvae of the freeze tolerant goldenrod gall fly, Eurosta solidaginis, that are often found in the same fields (or even on the same plants) as E. scudderiana, up-regulate HSPs both during the winter season when larvae are in diapause and in response to laboratory cold-acclimation (Zhang et al, 2011).…”