Transforming Translation: Impact of Clinical and Translational Science

Progress in Rare Diseases Research 2010–2016: An IRDiRC Perspective

“…Approximately half of all clinical trials were funded by companies (48%), the others supported by public institutions. These data serve as the foundation for much of the new work of the Constituent Committees aimed at identifying areas of need, prioritizing, and addressing those gaps via coordinated implementation activities, while taking into consideration the promising bedside‐to‐bench translational approach to increase the likelihood of success in drug development and clinical translation.…”

Advancing Clinical and Translational Science

“…The vision for the 2015–2020 American Society for Clinical Pharmacology and Therapeutics (ASCPT) strategic plan is that ASCPT's influence and leadership make it the authority on the science and practice of translational medicine, building on a foundation of clinical pharmacology and therapeutics (http://www.ascpt.org/About-ASCPT/ASCPT-Strategic-Plan). The vision for Clinical and Translational Science ( CTS ) is well‐suited for ASCPT . Our vision is to become the beacon and organizing principle for the field of translational medicine, as well as to provide a vehicle for ASCPT member publications.…”

“…Our vision is to become the beacon and organizing principle for the field of translational medicine, as well as to provide a vehicle for ASCPT member publications. The ASCPT definition of translational medicine serves as a framework for the CTS strategy. In brief, “From ASCPT's perspective, translational medicine is a multi‐faceted discipline with a focus on translational therapeutics.…”

Teaching Targeted Drug Discovery and Development to Healthcare Professionals

“…Pre‐course and post‐course surveys with knowledge questions related to the course were completed by 89.2% of students, and revealed significant increases in the knowledge of course domains. Additionally, the majority of the lecture ratings completed by 81.1% of students were 3 or greater, on a 5‐point scale …”

“…At the end of the course, students were required to complete a paper on a method/approach to design a therapy targeting one of the disease processes described in the class meetings. This course has been designed to provide a background that will prepare trainees for translational research in clinical pharmacology and basic science, which are being increasingly recognized as key components in the translational research continuum …”