Translation, adaptation, and initial validation of the Food Allergy Quality of Life Questionnaire – Parent Form (0–12 years) in Ukrainian language

Matsyura, Oksana; Menshykova, A. O.; Беш, Л.В.; Gutor, Taras; Kovalska, Oksana; Besh, Olesya; Sorokopud, O. O.; Lukyanenko, N. V.; Blok, B. M. J. Flokstra‐de

doi:10.5114/polp.2021.104828

polp

2021

DOI: 10.5114/polp.2021.104828

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Translation, adaptation, and initial validation of the Food Allergy Quality of Life Questionnaire – Parent Form (0–12 years) in Ukrainian language

Oksana Matsyura¹,

A. O. Menshykova²,

Л.В. Беш³

et al.

Abstract: Aim of the study: The objective of this study was aimed at the translation, adaption, and initial validation of the Food Allergy Quality of Life Questionnaire -Parent Form (FAQLQ-PF) (0-12 years) into Ukrainian language. Material and methods: Sixty patients with cow's milk allergy and their parents were involved in the study. The FAQLQ-PF translated into Ukrainian language and the Ukrainian version of the Food Allergy Independent Measure (FAIM) were used. Forward and backward translations were done. One indepe… Show more

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Cited by 3 publications

References 16 publications

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The Role of Immunohistochemical Markers in Predicting Recurrence or Death in Patients With Medular Thyroid Cancer

Duda¹,

Boyko²,

Slipetsky³

2021

PSSS MS

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Introduction. Medullary thyroid cancer (MTC) belongs to a class of rare neuroendocrine aggressive tumors and arises from parafollicular cells (C-cells). An important modern problem is the development of ways to predict the recurrence of this disease. The aim of the study is to determine the role of immunohistochemical tumor markers of medullary thyroid cancer in predicting recurrence or death. Materials and methods. The analysis of the prospective study included 22 patients with MTC, 5 of whom have developed a recurrence and 4 have died at the end of the 10-year (120 months) follow-up period. Immunohistochemical examinations were performed using monoclonal antibodies of tumor markers calcitonin, chromogranin A, vimentin and Ki-67. Results. The discrepancy between the data of histological and immunohistochemical examinations in MTC is 12.0%, which indicates the hyperdiagnosis of this nosology and argues the importance of performing immunohistochemical examinations to verify the diagnosis. Patients who had a recurrence of MTC had significantly (p <0.05) lower levels of calcitonin expression (5.00 [5.00; 5.00] points) compared with patients who did not relapse, where this figure was 6.00 [6.00; 7.00] points. In patients with MTC, an increase in calcitonin expression was significantly associated with an increase in chromogranin A expression (r = + 0.49, p = 0.02); a similar relationship was found for the proportions of immunopositive cells of these tumor markers: r = + 0.68, p = 0.001. At the same time, it was found that the increase in the level of calcitonin expression was apparently combined with the decrease in the level of Ki-67 expression (r = -0.52, p = 0.02). It was also found that the increase in the level of vimentin expression is combined with an increase in the expression (r = + 0.64, p = 0.001) and the proportion of immunopositive cells of chromogranin A (r = + 0.45, p = 0.038). Conclusions. Low levels of calcitonin expression are prognostically unfavorable markers for the recurrence of MTC. Specific tumor markers are important in the treatment process and for the dynamic monitoring of patients with MTC.

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The Role of Immunohistochemical Markers in Predicting Recurrence or Death in Patients With Medular Thyroid Cancer

Duda¹,

Boyko²,

Slipetsky³

2021

PSSS MS

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Food Hypersensitivity in Children Aged 0–3 Years of the Lviv Region in Ukraine: A Cross-Sectional Study

Matsyura¹,

Беш²,

Borysiuk³

et al. 2022

Front. Pediatr.

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Aim: To determine the prevalence and to estimate factors associated with food hypersensitivity in young children of the Lviv region in Ukraine.Methods: A prospective cross-sectional survey study was conducted between 2016 and 2017 in the Lviv region of Ukraine. A specially designed questionnaire about food hypersensitivity of young children developed and validated by M. J. Flokstra-de Blok was used after translation into the Ukrainian language. The questionnaire included 34 questions, grouped into general and detailed information. Parents of children aged 0–3 years were asked to complete the questionnaire at pre-schools and medical institutions.Results: Among 4,500 distributed questionnaires, 3,214 (71%) were completed and processed. Parents reported that 25% of their young children had food hypersensitivity. According to the survey the most common agents involved in food hypersensitivity in young children were cow's milk (34%), egg (28%), and wheat (24%). Hypersensitivity to milk occurred in 50% of children in the age group of 1–2 years. Regional differences associated with food hypersensitivity were also found. Namely, in the Carpathians, there was more hypersensitivity to fish (27%) and honey (22%) than in other regions, while hypersensitivity to soy was detected mostly in Lviv City residents (8.5%). Unknown causes of food hypersensitivity were highly reported (34%) in the Carpathians.Conclusion: Prevalence and some distinctiveness of food hypersensitivity revealed in four geographic and climate zones as well as in Lviv City have a considerable practical use for formulation of recommendations for children with food hypersensitivity.

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Adaptation, Translation and Validation of the Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF): The Malay Version

et al. 2021

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Food allergy has a significant impact on the quality of life (QoL) of children and can be measured using The Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF). This study aimed to adapt, translate the FAQLQ-PF into Malay and determine the validity and reliability of the translated version. This cross-sectional questionnaire validation study was conducted among parents of children (0 to 12 years old) with food allergies across five sites in Selangor and Kuala Lumpur, Malaysia. The FAQLQ-PF-Malay underwent cross-cultural adaptation, translation, validation (content, face and construct) and reliability assessment. Exploratory factor analysis, internal consistency and test-retest reliability analyses were used to examine its construct validity and reliability. Out of 150 children, the majority were between the age of 7 to 12 years old (41%) and were female (81%). Three subscales were identified, which were: (i) social and dietary implication, (ii) food anxiety and (iii) emotional and physical impact. Four items were eliminated because of weak factor loadings. The Cronbach’s alpha for each subscale ranged from 0.88 to 0.94, with an overall Cronbach’s alpha of 0.95. The intra-class correlation coefficient ranged from 0.54 (95% CI: 0.10–0.77) to 0.97 (95% CI: 0.90–0.99). The 26-item FAQLQ-PF-Malay retained the three-factor structure of the original FAQLQ-PF. The FAQLQ-PF-Malay is a valid and reliable tool to assess the QoL of Malaysian children with food allergies.

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Translation, adaptation, and initial validation of the Food Allergy Quality of Life Questionnaire – Parent Form (0–12 years) in Ukrainian language

Cited by 3 publications

References 16 publications

The Role of Immunohistochemical Markers in Predicting Recurrence or Death in Patients With Medular Thyroid Cancer

The Role of Immunohistochemical Markers in Predicting Recurrence or Death in Patients With Medular Thyroid Cancer

Food Hypersensitivity in Children Aged 0–3 Years of the Lviv Region in Ukraine: A Cross-Sectional Study

Adaptation, Translation and Validation of the Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF): The Malay Version

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