Transposition of Saccharomyces cerevisiae Ty1 retrotransposon is activated by improper cryopreservation

Stamenova, Radostina; Dimitrov, Milen; Stoycheva, Teodora; Pesheva, M.; Venkov, Pencho; Tsvetkov, Tsvetan

doi:10.1016/j.cryobiol.2008.03.007

Cited by 19 publications

(13 citation statements)

References 49 publications

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“…All samples from polluted regions gave positive results in Ty1 test with a fold increase ranging 7-12. The positive answers were confirmed in concentrations (= sample volume) dependent and kinetics experiments (Pesheva et al 2008). …”

Section: Response Of Ty1 Test To Environmental Pollutantsmentioning

confidence: 93%

“…We took advantage from these observations to further characterize Ty1 test and studied the effect of the free chenodeoxycholic (CDH) and lithocholic (LH) bile acids and the noncarcinogenic conjugated taurodeoxycholic (TDH) and glycodeoxycholic (GDH) bile acids (Pesheva et al 2008). The results obtained (Table 4) show that the carcinogenic CDH and LH bile acids induced positive responses in the Ty1 test, whereas the noncarcinogenic TDH and GDH bile acids give values close to the controls.…”

Section: Benzo(a)anthracene [B(a)a] and Benzo(b)anthracene [B(b)mentioning

confidence: 99%

“…Stress conditions, such as exposure to UV light (Rolfe & Banks 1986), low temperature treatment (Paquin & Williams 1984;Stamenova et al 2008), severe adenine starvation (Ribero-dos-Santos et al 1997) increase Ty1 transposition frequency. Chemical carcinogens can also increase transposition rate (Bradshow & McEntee 1989;Staleva & Venkov 2001).…”

Section: The Ty1 Transposition Testmentioning

confidence: 99%

“…Benzo ( Typical results from one out of six identical experiments a) Amount of superoxide anion (O2 ·-) in pM per one cell determined by the method described in Stamenova et al (2008) b) Cells treated only with NaN2 Table 2. Increased sensitivity of Ty1 test to metabolically activated B(a)P Similar increase in the values of Ty1 transposition rates was also found in kinetic experiments where cells were treated for periods of 15 to 90 minutes.…”

Section: Increased Sensitivity Of Ty1 Testmentioning

confidence: 99%

“…A] represent another pair of genotoxins studied in the Ty1 test (Dimitrov et al,2011;Pesheva et al 2008). B(a)A is assessed as carcinogenic for animals and humans while B(b)A is a non-carcinogenic mutagen (Salamone 1981).…”

Section: Benzo(a)anthracene [B(a)a] and Benzo(b)anthracene [B(b)mentioning

confidence: 99%

See 4 more Smart Citations

The Ty1 Retrotransposition Short-Term Test for Selective Detection of Carcinogenic Genotoxins

Stoycheva¹,

Pesheva²,

Dimitrov³

et al. 2012

Carcinogen

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Section: Response Of Ty1 Test To Environmental Pollutantsmentioning

confidence: 93%

Section: Benzo(a)anthracene [B(a)a] and Benzo(b)anthracene [B(b)mentioning

confidence: 99%

Section: The Ty1 Transposition Testmentioning

confidence: 99%

Section: Increased Sensitivity Of Ty1 Testmentioning

confidence: 99%

Section: Benzo(a)anthracene [B(a)a] and Benzo(b)anthracene [B(b)mentioning

confidence: 99%

See 3 more Smart Citations

The Ty1 Retrotransposition Short-Term Test for Selective Detection of Carcinogenic Genotoxins

Stoycheva¹,

Pesheva²,

Dimitrov³

et al. 2012

Carcinogen

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Impact of the Long-Term Maintenance Method of Brewer's Yeast on Fermentation Course, Yeast Vitality and Beer Characteristics

Matoulková

Sigler

2011

Journal of the Institute of Brewing

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The effect of the long-term maintenance method used with a brewer's yeast on its technological properties was determined in laboratory fermentation trials with a 12°P all-malt wort. The trials were performed at a constant temperature and under conditions of constant substrate concentration. Two cultures of a bottom fermenting yeast, Saccharomyces pastorianus RIBM 95, were tested -one culture was maintained by subculturing on wort agar slopes at 4°C and the other culture underwent a three year storage in liquid nitrogen at minus 196°C. Parameters under investigation included yeast vitality measured as acidification power (AP), fermentation time needed to reach an alcohol level of 4%, the yeast cell count, sedimentation of the yeast during the fermentation, and the production of beer flavour compounds in green beer. The yeast culture stored for three years in liquid nitrogen displayed a higher count of suspended cells, required a shorter time to attenuate the wort to produce 4% alcohol and produced a 1.5 to 2.5-fold higher concentration of a number of flavour compounds. The long-term storage method did not affect the sedimentation ability and vitality of the yeast strain tested.

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Current awareness on yeast

2009

Yeast

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In order to keep subscribers up‐to‐date with the latest developments in their field, this current awareness service is provided by John Wiley & Sons and contains newly‐published material on yeasts. Each bibliography is divided into 10 sections. 1 Reviews; 2 General; 3 Biochemistry; 4 Biotechnology; 5 Cell Biology; 6 Gene Expression; 7 Genetics; 8 Physiology; 9 Medical Mycology; 10 Recombinant DNA Technology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted. (6 weeks journals ‐ search completed 29th. Oct. 2008)

show abstract

Transposition of Saccharomyces cerevisiae Ty1 retrotransposon is activated by improper cryopreservation

Cited by 19 publications

References 49 publications

The Ty1 Retrotransposition Short-Term Test for Selective Detection of Carcinogenic Genotoxins

The Ty1 Retrotransposition Short-Term Test for Selective Detection of Carcinogenic Genotoxins

Impact of the Long-Term Maintenance Method of Brewer's Yeast on Fermentation Course, Yeast Vitality and Beer Characteristics

Current awareness on yeast

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