Treatment of carcinoma of the nasal vestibule by irradiation

Abstract

An analysis of 36 patients with squamous cell carcinoma of the nasal vestibule is made. The small lesions (T1 and T2) are highly curable by radiation therapy alone, with good functional and cosmetic results. The advanced lesions (T3), with bone destruction and metastases, are best treated by radical surgery with or without irradiation if the lesions are resectable. For the inoperable tumors, high dose megavoltage irradiation may offer palliation and, occasionally, an unexpected cure. Of 31 patients eligible for 3-year NED evaluation, 23 or 74% were alive and well without disease, after radiation therapy alone. For the T1, T2,and T3 lesions, the 3-year NED rates were 83,71, and 50%, respectively. A staging system for the primary disease is proposed.

Squamous Cell Carcinoma of the Nasal Vestibule Treatment Results

“…Authors have previously pointed to the significantly different prognosis of nasal cavity carcinomas, which is worse, and that of skin carcinomas, which is much better (10,14).…”

“…Carcinoma of the nasal vestibule has no internationally accepted TNM classification, but as done by DE JONG et coll. (l), the classification proposed by WANG (14) has been used retrospectively.…”

Cutaneous squamous cell carcinoma of the columella with an unusual revelation: a rare case report and a literature review of its staging and management challenges

“…According to many authors, this staging system predicts prognosis of nasal vestibule tumors more accurately [8][9][10][11]. It is relatively simple and includes only three stages (T1: involving only vestibule skin; T2: invading subcutaneous tissue and cartilage; T3: invading bone).…”

Brachytherapy of Squamous Cell Carcinoma of the Nasal Vestibule

“…Several systems have been used for classification of carcinomas of the nasal vestibule (10,12,13). Since the probability of tumor control correlates better with tumor volume than with the presence or absence of cartilage invasion (14), the classification should reflect tumor volume.…”