Squamous Cell Carcinoma of the Nasal Vestibule Treatment Results

Outcome and toxicity profile after brachytherapy for squamous cell carcinoma of the nasal vestibule

“…The 3‐year regional control rate of 93% is comparable with that reported by others, ranging from 95% to 100% in patients treated with brachytherapy alone . The higher rates of regional failure, ranging from 79% to 87% in series using external beam radiotherapy or combined surgery followed by external beam radiotherapy, can most likely be attributed to the higher tumor stage …”

“…Therefore, primary surgery is more suitable for salvage treatment of recurrent disease or the primary treatment of locally advanced tumors. The local control rate after external beam radiotherapy alone in T1 to T2 tumors ranges from 70% to 88% . A reasonable explanation for the better local control achieved with brachytherapy alone can be attributed to the shorter overall treatment time and the heterogeneous but partially higher dose given to a more conformal volume …”

“…For locally advanced tumors, surgery followed by radiotherapy is the treatment of choice . In Wang T1 to T2 or Union for International Cancer Control T1 to T2 tumors, radiotherapy has been favored because of the high local tumor control, ranging from 70% to 95%, and the good cosmetic outcome . Because of the easy access to the nasal vestibule, brachytherapy is an excellent treatment option, and shows even better tumor control than external beam radiotherapy .…”

“…4 In Wang T1 to T2 or Union for International Cancer Control T1 to T2 tumors, radiotherapy has been favored because of the high local tumor control, ranging from 70% to 95%, and the good cosmetic outcome. 2,3,[5][6][7] Because of the easy access to the nasal vestibule, brachytherapy is an excellent treatment option, and shows even better tumor control than external beam radiotherapy. [8][9][10] With the exception of Levendag et al, 8 most published series on brachytherapy are limited by the small number of patients and the combination of different treatment modalities.…”

Lymph node metastasis in nasal vestibule cancer: A review

“…The incidence of reported positive nodes in SCCNV is depicted in Table I. [4][5][6]11,12,16,[18][19][20][21][22][23][24][25][26][27][28][29]31,34,35 CONCLUSION SCCNV cancer is an uncommon isolated form of cancer, possibly originating in the mucocutaneous junction and is usually smoking induced. The incidence of synchronous or delayed regional metastases is higher than 20% in about half of the reported series.…”