Treatment of Chronic Methadone Dependence with Buprenorphine

Ahmadi, Jamshid; Internationals, Ommega

doi:10.15436/2471-061x-16-025

Cited by 2 publications

(2 citation statements)

References 10 publications

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“…Besides, buprenorphine is a partial agonist of mu-opioid receptor, so it decreases the level of suicidal desire, depression, dysphoria, anxiety, pain, and opioid withdrawal symptoms. In addition, buprenorphine is a strong kappa receptor antagonist, so it reduces suicidal thoughts, and depression [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29].…”

Section: Discussionmentioning

confidence: 99%

“Efficacy of Buprenorphine in the Treatment of Suicide”

Ahmadi,

2018

GJARM

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Background: Buprenorphine is currently used for the treatment of opioid use disorder and pain disorder. It could be an effective alternative option for the treatment of anxiety symptoms, depressive symptoms, self-destructive actions and suicidal ideations. However, it has a major potential for abuse and diversion that limits its application in these disorders. Objective: To explain the efficacy of buprenorphine in the treatment of Suicidal ideations. Conclusion: Buprenorphine can be an effective alternative option for the treatment of suicidal ideation.

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Section: Discussionmentioning

confidence: 99%

“Efficacy of Buprenorphine in the Treatment of Suicide”

Ahmadi,

2018

GJARM

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“…Focusing on mental disorders, substance use disorders, have been contemplated as a developing dilemma [31] . Concentrating on the published research works, opioids jointed disorders and stimulants allied problems have resulted more admissions to the psychiatric centers [32][33][34][35][36][37][38][39][40] . Now a days, buprenorphine is mainly used for the treatment of opioid withdrawal symptoms [41] .…”

Section: Introductionmentioning

confidence: 99%

Three high doses of buprenorphine in the treatment of prolonged and severe opium dependence: a new access

Ahmadi¹,

Internationals²

2017

JAS

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Background: Heavy and prolonged opium dependence is a progressing problem in the East. For the treatment of opium dependence, buprenorphine can be prescribed less frequently than daily due to its long half-life. Objective: To administered three high doses buprenorphine instead of daily use to reduce probability of buprenorphine dependence. Results: The prescription of three high doses of 32, 96 and 72 mg buprenorphine was tolerated conveniently. Administration of high doses of buprenorphine completely improved opium withdrawal symptoms. Discussion: The current work indicated that few high doses of buprenorphine, could be adequate and satisfactory for the improvement of heavy and prolonged opium dependence. Conclusions:We came to this result that administration of high dose buprenorphine looks to be convenient, acceptable and tolerable. More research studies should be of interest as high buprenorphine doses are getting more general clinically. We concluded that three doses of 32, 72 and 96 mg buprenorphine, could be adequate for the improvement of severe opium use disorder.

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Treatment of Chronic Methadone Dependence with Buprenorphine

Cited by 2 publications

References 10 publications

“Efficacy of Buprenorphine in the Treatment of Suicide”

“Efficacy of Buprenorphine in the Treatment of Suicide”

Three high doses of buprenorphine in the treatment of prolonged and severe opium dependence: a new access

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