N on-traumatic subarachnoid hemorrhage (SAH) usually caused by aneurysm rupture is a potentially devastating condition, feared both by patients and physicians. It is estimated that death from SAH occurs before hospital admission in 12% to 15% of cases¹. The epidemiology of SAH shows some particularities which professionals involved with health policies and the care of people with this disorder should be aware of. Age, gender, income, race and ethnicity have a significant impact on SAH presentation.There is a wide variation in the annual incidence of SAH in different regions of the world, from 2 cases per 100 000 population in China to 22.5 cases per 100 000 in Finland as shown by the WHO MONICA Stroke Study². In South and Central America the SAH incidence is reported to be 4.2 per 100 000 person-years³ with studies from Chile and Barbados indicating incidences of 6.2 per 100 000 per year (3.0-9.3) and 3.0 per 100 000 per year (1.0-5.0), respectively 4 . SAH incidence increases with age, with an average age of onset in adults of ≥50 years, being 1.24 times higher in women than in men 3,5 . In a Brazilian study the age-adjusted incidence for SAH was higher among females and increased progressively with age 6 . Mortality data obtained from the city of Sao Paulo Health Statistic System (PRO-AIM) identified SAH as a much more frequent cause of death among women when compared to men 7 . Race and ethnicity are relevant factors in SAH with Blacks and Hispanics having a higher incidence than white Americans
8. A study reviewing data on approximately one billion hospitalizations in the United States over a 30-year study period (1979-2008) identified 612 500 cases of SAH, which was more common in women and non-white persons9.The impact of income on SAH rates was reported in a recent systematic review of population-based studies, where the incidence of SAH ranged from 2 to 16 per 100 000, with a pooled age-adjusted incidence rate in low to middle-income countries almost double that found in high income countries 5 . Another study found a significant income-mortality association for SAH among US patients, which was absent among Canadian patients
10. The prevalence of intracranial aneurysms in the general population appears to be 2-5% and the frequency of unruptured aneurysms in angiographic and prospective autopsy series is approximately 3-4% 11 . In population-based studies of Latin American and the Caribbean 2-5% of all strokes were subarachnoid hemorrhage 4 . In a study of 2418 consecutive patients from 19 hospitals in the city of Fortaleza, Brazil, the frequency of admissions of subarachnoid hemorrhage patients was 6.0%
.The case fatality of SAH seems to remain high worldwide. However, mortality rates appear to have declined in industrialized nations over the past 25 years
13. Mortality rates vary widely across published epidemiological studies, ranging from 8% to 67% with a median mortality rate in the United States of 32% versus 43% in Europe and 27% in Japan14. In this issue of Arquivos de Neuropsiquiatria, Alcalá-Ce...