Triterpenoids of plants of the genus Abies Hill

Chemical constituents of Abies fabri

“…By further detailed analysis of its 2D NMR spectra and the literature data (Raldugin and Shevtsov, 1990;Raldugin et al, 1987), the structure of 5 was elucidated as methyl (25R)-3,7,23-trioxo-8,11,14-mariesiatrien-26-oate. Interestingly, compound 5 is the first example of a triterpene bearing a 8,11,14-mariesiatrien moiety.…”

Abiesatrines A–J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr

“…[3][4][5] To continuously explore the structurally and biologically novel chemical constituents from A. georgei, an intensive investigation was carried out, which led to the isolation of ten new (1-10) (Fig. 1) and 10 known (11)(12)(13)(14)(15)(16)(17)(18)(19)(20) triterpenes. Herein, we describe the isolation, structural elucidation, and antiinflammatory, as well as antitumor activities of these triterpenes.…”

“…new (1)(2)(3)(4)(5)(6)(7)(8)(9)(10) and ten known (11)(12)(13)(14)(15)(16)(17)(18)(19)(20) triterpenes. By comparison of the 1 H and 13 C NMR, and MS data with the published data, the known compounds were identified as (24R)-cycloartane-3b,24,25triol (11), 6,7 (24R)-cycloartane-3a,24,25-triol (12), 7 methyl (24Z)-26-carboxy-3,4-seco-cycloarta-4(29),24-dien-3-oate ( 13), 8 23-oxomariesiic acid B (14), 9 isofirmanoic acid (15), 9,10 (9b,24Z)-3,23dioxolanosta-7,24-dien-26-oic acid (16), firmanoic acid (17), 9 2a,3b,24-trihydroxy-12-ursen-28-oic acid (18), 11 dammarolic acid (19), 12 and ursolic acid (20). 13 The molecular formula C 30 H 46 O 4 of compound 1 was established on the basis of its positive HRESIMS at m/z 493.3293 [M+Na] + , indicating eight degrees of unsaturation.…”

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A novel spiro-lanostane (abiesatrine A, 1) was isolated from the aerial parts of Abies georgei together with 9 new (abiesatrines B-J, 2-10) and 10 known triterpenes (11)(12)(13)(14)(15)(16)(17)(18)(19)(20). The new structures were established by the extensive analysis of their spectroscopic data.

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Antibacterial, Antifungal, Insecticidal and Phytotoxic activities of Abies pindrow leaves

“…Most of them are flavonoids, fatty acid, alcohol, triterpenes and lignin's (Raldugin, et al, 1990). Some species have been used as folk medicines against various diseases such as indigestion, colds, stomachache, pulmonary and venereal diseases (Yesilada et al, 1995;Fujita, et al, 1995).…”