Tuberculose thyroïdienne

Oudidi, A.; Cherkaoui, A.; Zaki, Z.; Hachimi, Hicham; Alami, M. N. El

doi:10.1016/s0003-438x(05)82341-2

Cited by 8 publications

(2 citation statements)

References 17 publications

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“…Drainage or a surgical resection is required in the case of TTB associated with a large abscess. The medical treatment is based on the combination of three powerful antituberculous drugs: rifampin (R), isoniazid (H) and pyrazinamide (Z) [17,18]. In our case, we applied the protocol 2RHZ / 4 HR with a remarkable clinical improvement after 2 months of the start of treatment.…”

Section: Discussionmentioning

confidence: 99%

Thyroid Tuberculosis Mimicking an Anaplastic Carcinoma: A Rare Presentation

Anajar¹

2017

GJO

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Isolated tuberculosis of the thyroid gland is extremely rare with a few reported cases so far. When it does occur, it may seem difficult to diagnose due to non-specific and various clinical manifestations of tuberculous thyroiditis. Thyroid Tuberculosis simulating an anaplastic carcinoma appears to be the rarest and the most dangerous presentation. We report a case of a 70 year-old female who presented with a left lateral neck swelling for 4 months duration with no compression signs neither thyroid dysfunction nor other associated general signs. Cervical CT scan showed a left heterogeneous lateral neck mass invading the isthmus and the left thyroid lobe plunging into the sub clavicular region which was consistent with an anaplastic cancinoma. Histopathological examination was compatible with tuberculosis. The patient was then put under anti-tuberculous drug treatment for 6 months duration with a remarkable clinical improvement.

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Section: Discussionmentioning

confidence: 99%

Thyroid Tuberculosis Mimicking an Anaplastic Carcinoma: A Rare Presentation

Anajar¹

2017

GJO

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“…General features may not be present. Sometimes, the only clinical sign is an unexplained low-grade fever 6 , 13 . Early in evolution, hyperthyroidism can occur after parenchymal destruction and massive release of thyroid hormones.…”

Section: Discussionmentioning

confidence: 99%

Thyroid tuberculosis associated with papillary microcarcinoma: case report and review of literature

Elkrimi,

Rsaissi,

Bijou

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction: Thyroid tuberculosis (TB) is extremely rare. Infection may first occur in the thyroid gland or may be secondary to TB in other parts of the body. The diagnosis is rarely made clinically because the disease’s variable presentation often resembles that of a malignancy or an euthyroid nodular goiter. Case report: We present the case of a 40-year-old woman, who presented multiple thyroid nodules in both lobes. Two of these nodules were classified as EU-TIRADS V (European Thyroid Imaging and Reporting Data System). The ultrasound also found an adenopathy of the inferior part of the jugular lymphatic chain, in favor of malignancy. The histopathological examination after total thyroidectomy showed thyroid TB, associated to a papillary microcarcinoma of the right thyroid lobe, and the final examination of the adenopathy showed similar granulomas with caseous necrosis, and no signs of metastasis. Clinical discussion: Thyroid TB is very rare. Its diagnosis is difficult due to a lack of specific signs and symptoms, which is why the diagnosis is most commonly made on pathological examination after thyroid surgery. It is well known that mycobacterial infection creates an environment of chronic and persistent inflammation, with possible DNA damage. This can create a microenvironment that is highly conductive to carcinogenesis, which could explain the discovery of papillary microcarcinoma in addition to thyroid TB in our patient. Conclusion: This report presents a rare case of malicious growth development of thyroid nodules and thyroid TB. Therefore, physicians must always be vigilant when managing thyroid nodules, as there is always the possibility of malignant lesions associated to an inflammatory or infectious cause.

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