Tuning the interactions of decavanadate with thaumatin, lysozyme, proteinase K and human serum proteins by its coordination to a pentaaquacobalt(ii) complex cation

Abstract

Inorganic functionalization of the decavanadate anion promotes a different type of interaction with model proteins thaumatin, lysozyme, proteinase K, human serum albumin and transferrin.

(NH4)2[Ni(H2O)6]2V10O28 ⋅ 4H2O; Structural Analysis and Bactericidal Activity against Pathogenic Gram Negative Bacteria

“…spectrum at 952 cm À 1 is due to stretching vibration of the terminal VÀ O bonds υ(VÀ O t ) (O t = terminal oxygen), [44] while the antisymmetric stretching vibrations of the bridging oxygen O b -vanadium bonds υ as (VÀ O b ) exist at 829, 809 and 741 cm À 1 [45][46][47] and the symmetric stretching vibrations of the same bonds υ s (VÀ O b ) appear at lower wavenumbers at 574, 518 and 456 cm À 1 . [48] A broad band is located around 3396 cm À 1 could be assigned to asymmetric and symmetric vibrations υ(OÀ H) of lattice water, [44,49,50] whereas another sharp band is located around 1613 cm À 1 due to the water δ(HÀ OÀ H) bending vibrational modes.…”

“…[51] The broad absorption observed in the region around 3192 cm À 1 and the peak at 1420 cm À 1 are attributed to symmetric and asymmetric stretching vibrations of the NÀ H groups of the tetrahedral ammonium cation. [47,51] The thermogram of (NH…”

Selective Hydrolysis of Transferrin Promoted by Zr-Substituted Polyoxometalates

“…Depending on their structural, physical, and chemical properties POMs have different applications in various fields of material science, photochemistry, medicine, and catalysis [ 22 , 23 , 24 ]. The interactions of POMs with proteins have been studied by different approaches and provided insight on the possible role of POMs in biological systems and their potential use in medicine [ 24 , 25 , 26 , 27 , 28 , 29 , 30 ]. The Keggin, Wells-Dawson and Lindqvist type of POMs are most frequently investigated POMs, and their structure can be substituted with strongly Lewis acidic metals such as Zr(IV), Hf(IV) or Ce(IV).…”

Kinetic Studies of Sodium and Metforminium Decavanadates Decomposition and In Vitro Cytotoxicity and Insulin- Like Activity

“…In biological studies, buffer solutions are extensively used, although just a few studies have addressed the speciation of the decomposition products of the decavanadate compounds in such reaction media. The decomposition of the decameric species at neutral pH can be followed by 51 V NMR showing a decrease in the peaks associated with the three magnetic independent vanadium nuclei of the decavanadate V A , V B and V C (Figure 1), albeit an increase of the signals for the metavanadate peak [H 2 VO 4 ] − (V 1 ) and the appearance of the orthovanadates species signals like [H 2 V 2 O 7 ] 2− (V 2 ), [V 4 O 12 ] 4− (V 4 ) and [V 5 O 15 ] 5− (V 5 ) [12][13][14]. Moreover, monomeric vanadate is always present in decavanadate solutions at neutral pH [15].…”

“…In this work, we have studied the kinetics of the decomposition of 0.5 and 1 mM sodium decavanadate (NaDeca) and metforminium decavanadate (MetfDeca) in Dulbecco's modified Eagle's medium (DMEM) solution at pH 7.4 by 51 V NMR, with the aim to understand the medium and the vanadium concentration effects in both, the decomposition rate and the influence in the ratio of the final products, namely V 1 , V 2 , V 4 and V 5 . To our knowledge, the ammonium decavanadate compound decomposition in MES; MES = 2-(N-morpholino)ethanesulfonic acid by 51 V NMR is the only report that describes the decomposition reaction [14]. Thus, NaDeca stability has not been extensively studied in buffer solutions.…”