Tuning the Morphological, Optical, and Antimicrobial Properties of α-Ag₂WO₄ Microcrystals Using Different Solvents

Abstract

New, effective antimicrobial agents are constantly being evaluated for addressing the increased prevalence of bacterial and fungal infections and emerging drug resistance. In this study, α-Ag2WO4 microcrystals were prepared by controlled coprecipitation (90 °C for 10 min) in different solvents (e.g., water, an alcoholic solution, and an ammoniacal solution). From the X-ray diffraction results, the newly synthesized α-Ag2WO4 microcrystals are well-indexed to the orthorhombic structure. Two morphologies were seen by field-emission scanning electron microscopy: microrods in the alcoholic solution and flowerlike structures in water and the ammoniacal solution. The synthesized α-Ag2WO4 microcrystals exhibited antimicrobial activity against Candida albicans, Escherichia coli, and methicillin-resistant Staphylococcus aureus. In addition, the antibacterial performance of the α-Ag2WO4 samples as a function of their structural and morphological features was discussed.

Rational Design of W-Doped Ag3PO4 as an Efficient Antibacterial Agent and Photocatalyst for Organic Pollutant Degradation

“…Antibacterial activity probes were performed according to the protocol previously described. 74 Briefly, MRSA cells were cultured from the frozen stock onto Mueller–Hinton agar plates and incubated at 37 °C for 24 h. Colonies of fresh cells were transferred to tryptic soy broth (TSB) and incubated until reaching the mid-log stage of microbial growth. The minimal inhibitory and minimal bactericidal concentration (MIC/MBC) susceptibility tests were performed using the broth microdilution method of the Clinical and Laboratory Standards Institute, documents M27-A3 (2008), 75 with some modifications.…”

Promising effects of silver tungstate microcrystals on fibroblast human cells and three dimensional collagen matrix models: A novel non-cytotoxic material to fight oral disease

“…The microcrystal synthesis process triggers the oxidation of silver into α-Ag 2 WO 4 . The oxidized silver [Ag + ] concentration in the microcrystal structure was calculated using the following equation: Silver content in the MFC of α-Ag 2 WO 4 microcrystals = MFC of α-Ag 2 WO 4 microcrystals (μmol/ mL) × 10 −6 /Molecular Weight of each chemical element in the molecular structure of α-Ag 2 WO 4 [25].…”

“…The experimental groups were established according to the MFC obtained from Candida albicans (C. albicans) ATCC 90028. Previously published MFC data were used to determine the lowest concentration capable of killing 100% of fungi, and this value was 7.81 μg/mL (C2) [25]. Further concentrations were used as experimental references: 10 times diluted (C1) and 10 times concentrated (C3).…”

In Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals

“…Silver nanoparticles (AgNPs) have been shown to have significant antimicrobial activity against planktonic cells and biofilms of Candida glabrata, Candida tropicalis, Staphylococcus aureus, and methicillin-resistant Staphylococcus aureus (MRSA) [13][14][15][16][17]. Recent studies have shown the antimicrobial effect of Ag as a microcrystal [18][19][20][21]. The ability of Ag 2 WO 4 in fighting Candida albicans is related to the imperfect and crystalline patterns of atom arrangements in its orthorhombic structure and good photocatalytic capacity under visible light [21].…”

“…Recent studies have shown the antimicrobial effect of Ag as a microcrystal [18][19][20][21]. The ability of Ag 2 WO 4 in fighting Candida albicans is related to the imperfect and crystalline patterns of atom arrangements in its orthorhombic structure and good photocatalytic capacity under visible light [21]. Also, Ag particles can increase the interaction and penetration into the cell membrane and, consequently, their antimicrobial activity [13,16,17].…”