Turn-on fluorescent glutathione detection based on lucigenin and MnO₂ nanosheets

Abstract

A GSH sensing platform using lucigenin as a fluorescent probe in the presence of MnO2 nanosheets was reported for the first time.

Crossing the blood–brain barrier with carbon dots: uptake mechanism andin vivocargo delivery

“…A refers to the absorbance, F is the integrated area under the PL emission curve, and η is the refractive index of the solvent used for the measurements. Quinine sulphate ( Φ = 54%) in 0.1 M H 2 SO 4 ( η = 1.33) 27 and lucigenin ( Φ = 67%) 28 in DI-water were used as two independent standards for QY calculations of GluCDs dispersed in DI-water ( η = 1.33). Absorbance of GluCDs was measured at a concentration in which the absorption peak was kept under 0.05 at 350 nm and the same concentration was used for PL emission measurements.…”

Chemiluminescence Detection in the Study of Free-Radical Reactions. Part 2. Luminescent Additives That Increase the Chemiluminescence Quantum Yield

“…It can also be applied to the study of xanthine and hypoxanthine oxidation by xanthine oxidase [ 49 ] to detect the superoxide radical formed as the result of NADPH oxidase activity [ 49 , 50 , 51 , 52 ] and in ether mitochondria of intact cells [ 53 ] or an isolated mitochondrial suspension [ 54 , 55 ]. Lucigenin-based techniques have recently been developed to detect dopamine [ 56 ] and glutathione [ 57 ]. In both cases, lucigenin was part of a relatively complex test system (the hypothetical mechanisms of lucigenin-dependent chemiluminescence activation in various systems are discussed in detail in the review [ 6 ]).…”

Biodegradable Fluorescent SiO2@MnO2-Based Sequence Strategy for Glutathione Sensing in a Biological System and Synergistic Theragnostics to Cancer Cells

“…The MnO 2 could shield the short-wavelength upconversion fluorescence without affecting near-infrared fluorescence, which realizes the ratio sensing based on GSH. Besides, various configurations of MnO 2 nanostructures are also used to develop GSH activated procedures, such as MnO 2 nanoparticles, honeycomb MnO 2 , , , MnO 2 nanosheets, , MnO 2 nanowires, and so on. Hence, MnO 2 nanomaterials provide diversified programs to construct an off–on fluorescence sensing strategy for highly sensitive monitoring of GSH.…”