A patient with a history of cardiac arrest and ischemic cardiomyopathy was referred for a secondary prevention implantable cardiac defibrillator. Later, the patient was admitted because of multiple shocks. Device electrograms revealed inappropriate shocks as a result of double-sensing in the ventricular channel. Chest radiography also revealed lead dislodgement along with device rotation along its axis. Twiddler's syndrome occurs in obese women with loose, fatty subcutaneous tissue, and is characterized by the rotation of the pulse generator on its long axis with subsequent coiling of the pacemaker leads. Using active fixation leads, sub-pectoral implantation should be considered in obese patients to prevent progressive generator displacement inside the subcutaneous pouch and eventually progressive lead displacement. In this case report, we will discuss the differential diagnosis of double sensing and inappropriate therapies, as well as prevention and management of lead dislodgement.