Two forms of déjà vu experiences in patients with epilepsy

Adachi, Naoto; Akanuma, Nozomi; Ito, Masumi; Adachi, Takuya; Takekawa, Yoshikazu; Adachi, Yasushi; Kanemoto, Kousuke; Kato, Masaaki

doi:10.1016/j.yebeh.2010.02.016

Cited by 37 publications

(38 citation statements)

References 35 publications

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“…Though not formally assessed, many epilepsy patients reported being able to distinguish between seizure-related and non-seizure related déjà vu, a phenomenon that has previously been described 15. Ictal déjà vu was associated with more unpleasant emotions and physical symptoms than physiological déjà vu, which is in keeping with previous findings 1 7 15 16…”

Section: Discussionsupporting

confidence: 84%

Is there anything distinctive about epileptic deja vu?

Warren‐Gash

Zeman

2013

Journal of Neurology, Neurosurgery & Psychiatry

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Section: Discussionsupporting

confidence: 84%

Is there anything distinctive about epileptic deja vu?

Warren‐Gash

Zeman

2013

Journal of Neurology, Neurosurgery & Psychiatry

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“…It remains to be seen, however, whether the same neurophysiological mechanism underlies nonpathological DV. Large-scale surveys reveal a higher incidence of DV in healthy (76 %) relative to epileptic populations (63 %; Adachi et al 2010). Recent investigations also show that while these two manifestations of DV are phenomenologically similar (Warren-Gash and Zeman 2014), they are associated with distinct neuroanatomical substrates (Brázdil and Zeman 2013;Labate et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Structural covariance mapping delineates medial and medio-lateral temporal networks in déjà vu

Shaw

Mareček

Brázdil

2015

Brain Imaging and Behavior

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Déjà vu (DV) is an eerie phenomenon experienced frequently as an aura of temporal lobe epilepsy, but also reported commonly by healthy individuals. The former pathological manifestation appears to result from aberrant neural activity among brain structures within the medial temporal lobes. Recent studies also implicate medial temporal brain structures in the non-pathological experience of DV, but as one element of a diffuse neuroanatomical correlate; it remains to be seen if neural activity among the medial temporal lobes also underlies this benign manifestation. The present study set out to investigate this. Due to its unpredictable and infrequent occurrence, however, non-pathological DV does not lend itself easily to functional neuroimaging. Instead, we draw on research showing that brain structure covaries among regions that interact frequently as nodes of functional networks. Specifically, we assessed whether grey-matter covariance among structures implicated in non-pathological DV differs according to the frequency with which the phenomenon is experienced. This revealed two diverging patterns of structural covariation: Among the first, comprised primarily of medial temporal structures and the caudate, grey-matter volume becomes more positively correlated with higher frequency of DV experience. The second pattern encompasses medial and lateral temporal structures, among which greater DV frequency is associated with more negatively correlated grey matter. Using a meta-analytic method of co-activation mapping, we demonstrate a higher probability of functional interactions among brain structures constituting the former pattern, particularly during memory-related processes. Our findings suggest that altered neural signalling within memory-related medial temporal brain structures underlies both pathological and non-pathological DV.

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“…A DV aura occurs in 10% of patients with TLE [11]; DV as a sign is present in 2/3 of patients with idiopathic generalized epilepsy [12]. In our previous paper, we also describe DV in patients with idiopathic generalized epilepsy [13].…”

Section: Introductionmentioning

confidence: 89%

Déjà vu phenomenon-related EEG pattern. Case report

Власов

Chervyakov

Gnezditskii

2013

Epilepsy & Behavior Case Reports

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BackgroundDéjà vu (DV, from French déjà vu — “already seen”) is an aberration of psychic activity associated with transitory erroneous perception of novel circumstances, objects, or people as already known.ObjectiveThis study aimed to record the EEG pattern of déjà vu.MethodsThe subjects participated in a survey concerning déjà vu characteristics and underwent ambulatory EEG monitoring (12–16 h).ResultsIn patients with epilepsy, DV episodes began with polyspike activity in the right temporal lobe region and, in some cases, ended with slow-wave theta–delta activity over the right hemisphere. There were no epileptic discharges in healthy respondents during DV.ConclusionTwo types of déjà vu are suggested to exist: “pathological-epileptic” déjà vu, characteristic of patients with epilepsy and equivalent to an epileptic seizure, and “nonpathological-nonepileptic” déjà vu, which is characteristic of healthy people and psychological phenomenon.

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Two forms of déjà vu experiences in patients with epilepsy

Cited by 37 publications

References 35 publications

Is there anything distinctive about epileptic deja vu?

Is there anything distinctive about epileptic deja vu?

Structural covariance mapping delineates medial and medio-lateral temporal networks in déjà vu

Déjà vu phenomenon-related EEG pattern. Case report

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