Two New Antiinflammatory Triterpene Saponins from the Egyptian edicinal Food Black Cumin (Seeds of Nigella sativa)

Elbandy, Mohamed; Kang, Ok‐Hwa; Kwon, Dong‐Yeul; Rho, Jung‐Rae

doi:10.5012/bkcs.2009.30.8.1811

Cited by 9 publications

(1 citation statement)

References 22 publications

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“…The seeds contain fixed and volatile oils, proteins, flavonoid glycosides (kaempferol 3- O -β-D-glucopyranosyl-(1→2)- O -β-D-galactopyranosyl-(1→2)- O -β-D-glucopyranoside), alkaloids (mainly magnoflorine), and saponins (sieboldianoside A, tauroside H2, tauroside G3, decaisoside D, sapindoside B, tauroside E). The most important active compounds were thymoquinone, thymohydroquinone, and dithymoquinone [ 77 , 78 , 79 ]. Salvia and Nigella seeds contain terpenoids and quinones that are reported to interact with opiate receptors [ 80 ].…”

Section: Resultsmentioning

confidence: 99%

Applicability of LC-QToF and Microscopical Tools in Combating the Sophisticated, Economically Motivated Adulteration of Poppy Seeds

Avula

Katragunta

Adams

et al. 2023

Foods

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Morphine and codeine are the two principal opiates found in the opium poppy (Papaver somniferum L.) and are therapeutically used for pain management. Poppy seeds with low opiates are primarily used for culinary purposes due to their nutritional and sensory attributes. Intentional adulteration of poppy seeds is common, often combined with immature, less expensive, exhausted, or substituted with morphologically similar seeds, viz., amaranth, quinoa, and sesame. For a safer food supply chain, preventive measures must be implemented to mitigate contamination or adulteration. Moreover, the simultaneous analysis of P. somniferum and its adulterants is largely unknown. Pre- and post-processing further complicate the alkaloid content and may pose a significant health hazard. To address these issues, two independent methods were investigated with eight botanically verified and fifteen commercial samples. Microscopical features were established for the authenticity of raw poppy seeds. Morphine, codeine, and thebaine quantities ranged from 0.8–223, 0.2–386, and 0.1–176 mg/kg, respectively, using LC-QToF. In most cases, conventional opiates have a higher content than papaverine and noscapine. The analytical methodology provided a chemical profile of 47 compounds that can be effectively applied to distinguish poppy seeds from their adulterants and may serve as an effective tool to combat ongoing adulteration.

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Section: Resultsmentioning

confidence: 99%