Two new flavone glycosides from Chenopodium ambrosioides growing wildly in Egypt

Abstract

Chenopodium ambrosioides (Chenopodiaceae) growing wildly in Egypt was subjected to antioxidant-guided phytochemical investigation and the EtOAc fraction afforded the two new flavone glycosides; scutellarein-7-O-α-rhamnopyranosyl-(1→2)-α-rhamnopyranosyl-(1→2)-α-rhamnopyranoside (1) and scutellarein-7-O-α-rhamnopyranosyl-(1→2)-α-rhamnopyranoside (2). In addition, the in vitro antioxidant activities of the plant alcohol extract, CHCl 3 fraction, EtOAc fraction and isolates were studied.

A New Kaempferol Glycoside with Antioxidant Activity from Chenopodium ambrosioides Growing in Egypt

“…Reviewing the literature revealed that the different parts of C. ambrosioides showed numerous biological activities i.e., antimicrobial 16,17 , cytotoxicity 18 , antioxidant 19 , larvicidal 20 , antidiabetic 4 , antiparasitic 21 , antiviral 22 , and molluscidal 23 . Moreover, from the phytochemistry point of view C. ambrosioides is known to contain secondary metabolites i.e., saponins 24 , terpenoids 2,25,26 , flavonol glycosides 27,28 , flavone glycosides 29 , and chenopodiumamines & chenopodiumoside 30 . The accumulation of the reactive free radicals in our bodies led to phenomena known as oxidative stress which represent the imbalance between the endogenous antioxidant molecules in our bodies and the extent of such species.…”

Characterization of Polyphenols from Chenopodium botrys after Fractionation with Different Solvents and Study of Their In Vitro Biological Activity

“…Metabolism in various species of Chenopodiaceae is known to synthesize mainly glycosides of quercetin, kaempferol and isorhamnetin. The carbohydrates that are involved in the structure of glycosides are glucose, galactose, rhamnose and apiose [ 18 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ].…”