Two new penterpenoid saponins and a new diterpenoid glycoside from Hemsleya chinensis

Terpenoids with cytotoxic activity from the branches and leaves of Pyrus pashia

“…The main difference between them was that compound 1 bear an oxygenated CH 2 group at d than seven methyl groups as in maslinic acid. Meanwhile, the chemical shifts of double bond at d C 127.3 (d, C-12), 139.4 (s, C-13) as well as d C 47.8 (t, C-14) and d C 24.0 (t, C-15) in 1 were not same as common oleanane-type triterpenoids such as oleanolic acid, maslinic acid, echinocystic acid, gypsogenin acid (Hou et al, 2009;Rubio-Moraga et al, 2011;Zeng et al, 2011;Song et al, 2015), which may be to the inductive effect of the hydroxyl group substituted at C-27 in 1. Comparison of the NMR data of 1 with the known compound 3b, 27-dihydroxyolean-12-en-28-oic acid (Jiang et al, 1996) and HMBC correlations from d H 4.06 (d, J = 12.0 Hz, H-27) to d C 40.3 (s, C-8) and d C 24.0 (t, C-15) further supported the presence of OH-27 (Fig.…”

Cytotoxicity and molecular-docking approach of a new rosane-type diterpenoid from the roots of Euphorbia nematocypha

“…The n -BuOH extract (560.4 g) was presented to a chromatographic column (120 cm × 22 cm) filled with silica gel (9.0 kg) and eluted with CH 2 Cl 2 /MeOH (20:1, 10:1, 5:1, and 2:1 v/v ; 80-L each) to afford four fractions (E1, E2, E3, and E4). The weight of E1, E2, E3, and E4 was 10.00 g, 25.37 g, 57.00 g, and 78.08 g, respectively ( Song et al, 2015 ).…”

“…The n-BuOH extract (560.4 g) was presented to a chromatographic column (120 cm × 22 cm) filled with silica gel (9.0 kg) and eluted with CH 2 Cl 2 /MeOH (20:1, 10:1, 5:1, and 2:1 v/v; 80-L each) to afford four fractions (E1, E2, E3, and E4). The weight of E1, E2, E3, and E4 was 10.00 g, 25.37 g, 57.00 g, and 78.08 g, respectively (Song et al, 2015). F2 (172.22 g) was submitted to a column (90 cm × 8 cm) filled with C 18 reversed-phase gel (805.0 g) and eluted with MeOH/ H 2 O (40:60, 70:30, and 100:0 v/v; 10-L each) in turn, and three fractions (F2a, F2b, and F2c) were obtained.…”

Study on extraction technology and antioxidant activity of total alkaloids from Hemsleya chinensis based on orthogonal design and BP neural network

“…Traditional Chinese medicine has traditionally used the tubers of these plants. This genus has been analyzed and evaluated for its phytochemical composition, which included diterpenes, alkaloids, and cucurbitane-type triterpene [ [10] , [11] , [12] , [13] ]. Additionally, this genus contains alkaloid constituents [ 14 ].…”