Übelkeit und Erbrechen nach gynäkologischen Laparoskopien

Möllhoff, T.; Burgard, G.; Prien, T.

doi:10.1055/s-2007-996441

Cited by 4 publications

(3 citation statements)

References 2 publications

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“…187/269 4.9 (3.7-7.1) [1], [83], [110], [112], [114], [116][117][118][119] Propofol for maintenance-late events Nausea [38], [73], [88], [96], [102], [107], [108], [120], [122][123][124][125] 165/217 140/219 8.3 (4.9-28) [4], [73], [88], [102], [107], [108], [122] Any event The event rate scatters ( fig. 1) suggested improvement with propofol over control mainly for early outcomes when propofol was used for maintenance, and also suggested homogeneity for all data sets.…”

Section: -255mentioning

confidence: 99%

Propofol anaesthesia and postoperative nausea and vomiting: quantitative systematic review of randomized controlled studies.

Tramèr¹,

Moore²,

McQuay³

1997

British Journal of Anaesthesia

273

112

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We have analysed randomized controlled studies which reported the incidence of postoperative nausea and vomiting (PONV) after propofol anaesthesia compared with other anaesthetics (control). Cumulative data of early (0-6 h) and late (0-48 h) PONV were recorded as occurrence or non-occurrence of nausea or vomiting. Combined odds ratio and number-needed-to-treat were calculated for propofol as an induction or maintenance regimen, early or late outcomes, and different emetic events. This was performed for all control event rates and within a range of 20-60% control event rates. We analysed 84 studies involving 6069 patients. The effect of propofol on PONV was dependent mainly on the method of administration, time of measurement and range of control event rates. When all studies were included the number-needed-to-treat to prevent PONV with propofol was more than 9 when used for induction of anaesthesia and at best 6 when used for maintenance. Within the 20-60% control event rate range, best results were achieved with propofol maintenance to prevent early PONV: the number-needed-to-treat to prevent early nausea was 4.7 (95% confidence interval 3.8-6.3), vomiting 4.9 (4-6.1) and any emetic event 4.9 (3.7-7.1). Within the 20-60% control event rate, of five patients treated with propofol for maintenance of anaesthesia, one will not vomit or be nauseated in the immediate postoperative period who would otherwise have vomited or been nauseated. This may be clinically relevant. In all other situations the difference between propofol and control may have reached statistical significance but was of doubtful clinical relevance. Treatment efficacy should be established within a defined range of control event rates for meaningful estimates of efficacy and for comparisons.

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Section: -255mentioning

confidence: 99%

Propofol anaesthesia and postoperative nausea and vomiting: quantitative systematic review of randomized controlled studies.

Tramèr¹,

Moore²,

McQuay³

1997

British Journal of Anaesthesia

273

112

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“…Mit einer systematischen computergestützten Literaturrecherche der Medline Literaturdatenbank und der Cochrane-Library wurden Studien gesucht, die Informationen über das Auftreten von PONV zu bestimmten Phasen des In einer Reihe von Originalpublikationen [2-4, 8,12,13,16,18,19] wie auch in Übersichtsarbeiten [17] Objective. Several studies suggest that the menstrual cycle has an impact on postoperative nausea and vomiting (PONV).However, many studies report inconsistent results.…”

Section: Methodikunclassified

Menstruationszyklus in der postoperativen Phase

Eberhart¹,

Morin²,

Georgieff³

2000

Der Anaesthesist

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“…In eigenen Untersuchungen konnten wir zeigen, daß sowohl Diflunisal (l9), Naproxen (23) aber auch Diclofenac und Azapropazon, sowie die Kombination aus letzteren beiden (24) So wird die Häufigkeit dieser Nebenwirkungen nach Laparoskopien aufgrund des Pneumoperitoneurns mit bis zu 77% angegeben (12). Neuere Untersuchungen zeigen nach gynäkologisch-laparoskopischen Eingriffen eine Abhängigkeit von der Phase des Menstruationszyklus (17). Da wir die Zykiusphase nicht erhoben haben, können wir hierzu keine Aussagen machen.…”

Section: Strumaresektionenunclassified

Untersuchungen zum differenzierten Einsatz von Nichtopioiden zur postoperativen Analgesie II - Quantifizierung des analgetischen Effektes der Kombination von Metamizol plus Diclofenac mittels der patientenkontrollierten Analgesie

Steffen

Druck²,

Krinn³

et al. 1996

Anästhesiol Intensivmed Notfallmed Schmerzther

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Übelkeit und Erbrechen nach gynäkologischen Laparoskopien

Abstract: The incidence of PONV is significantly higher when patients undergo laparoscopy during the first 8 days of the menstrual cycle. When compared to isoflurane, propofol results in a significantly lower incidence of PONV and postoperative shivering and a lower occurrence of postoperative pain.

Cited by 4 publications

References 2 publications

Propofol anaesthesia and postoperative nausea and vomiting: quantitative systematic review of randomized controlled studies.

Propofol anaesthesia and postoperative nausea and vomiting: quantitative systematic review of randomized controlled studies.

Menstruationszyklus in der postoperativen Phase

Untersuchungen zum differenzierten Einsatz von Nichtopioiden zur postoperativen Analgesie II - Quantifizierung des analgetischen Effektes der Kombination von Metamizol plus Diclofenac mittels der patientenkontrollierten Analgesie

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