Über die isolierung von O-methyl-dauricin aus colubrina asiatica

Revised Structure of Phaeantharine

“…The ms of the reduced base showed at both 70 and 12 eV only a very small M+ at m/e 638 with the base peak at m/e 206. This is identical to the ms behaviour of O-methyldauricine 7 (4). This was confirmed by fd-ms, which showed one major peak at m/e 639 (M++H) for the reduced phaeantharine.…”

Chemistry,13C-NMR Study and Pharmacology of Two Saponins from Colubrina asiatica

“…The leaves, which are used in the Philippines as a decoction for the treatment of skin deseases [1] and in Samoa and the Fijdi Islands as a convenient detergent ("Vuso levu") [2], have not been chemically investigated. From the bark of this plant the tetrahydroisochinolin derivative 0-methyl-dauricine has been isolated [3]. Pharmacological studies, performed with the essential oil of the fruits showed a blood pressure lowering and a spasmolytic activity [4].…”

Antifungal Jujubogenin Saponins from Colubrina retusa

“…During our screening program searching for antifungal agents from higher plants, Colubrina retusa, a rhamnaceous plant growing in Venezuela, was selected for bioassay-guided fractionation on the basis of its activity against Cryptococcus neoformans. It has been reported that some species of Colubrina contain saponins, [1][2][3][4] alkaloids, [5][6][7][8][9] triterpenes, 10,11 phenolics, 12 and essential oils; 13 however, no work has been reported on the chemical constituents of C. retusa. In this paper, we present the isolation, structure determination, and antifungal activity of three jujubogenin saponins (1)(2)(3) from the stems of this plant.…”