Ueber das Vorkommen des Trimethylamins in der Häringslake

Trimethylamine (TMA) and its N-oxide (TMAO) are ubiquitous in prokaryote and eukaryote organisms as well as in the environment, reflecting their fundamental importance in evolutionary biology, and their diverse biochemical functions. Both metabolites have multiple biological roles including cell-signaling. Much attention has focused on the significance of serum and urinary TMAO in cardiovascular disease risk, yet this is only one of the many facets of a deeper TMA−TMAO partnership that reflects the significance of these metabolites in multiple biological processes spanning animals, plants, bacteria, and fungi. We report on analytical methods for measuring TMA and TMAO and attempt to critically synthesize and map the global functions of TMA and TMAO in a systems biology framework.

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“…TMA was first isolated and formally identified by Hofmann in early 1852 . TMA, like most amines, has a strong smell.…”

Section: Analytical Measurement Of Methylaminesmentioning

confidence: 99%

Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide

et al. 2022

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Amine

Karrer¹

1976

Konstitution Und Vorkommen Der Organischen Pflanzenstoffe (Exclusive Alkaloide)

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Trimethylamine—The Extracorporeal Envoy

Mitchell

Smith

2016

CHEMSE

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One of the most widespread and efficient mechanisms that has evolved to enable communication between discrete and spatially separate living organisms is the use of specific chemical messengers. The organoleptic properties of certain molecules, even at concentrations that do not necessarily evoke a conscious response, have been exploited to transmit information across relatively large distances. The trimethylated derivative of ammonia is one such molecule that is ideally suited to this function and several species are known to respond to its presence. This review uniquely collects together and integrates widely dispersed data to show that trimethylamine also may serve a communicatory role in man, with its influence extending outside of the body.

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Ueber das Vorkommen des Trimethylamins in der Häringslake

Cited by 3 publications

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Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide

Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide

Amine

Trimethylamine—The Extracorporeal Envoy

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