How is the doctrine of ministerial responsibility applied in the decisions of German ministers (not) to resign? This question arises from an empirical puzzle as well as from a theoretical contradiction. Despite the prominent principle of ministerial responsibility, empirically, the ‘personal consequences' of ministerial scandals in their area of responsibility, display a large variance. Some ministers resign because of rather trifling affairs, others stay in office in spite of serious scandals. Taking into consideration the delegation relationship between the executive and the parliament, in view of the principal‐agent theory, a minister's resignation due to major political or personal misconduct is to be expected. On the other hand, the actual constitutional configuration of ministerial responsibility casts theoretical doubts on the ministerial loss of office. The quantitative analysis of 133 resignation issues in the years 1949 to 2009 reveals that ministerial responsibility bears no relevance to the decision whether to resign or not. Indeed, when the cause of the resignation issue is directly connected to ministerial responsibility, the probability of a resignation even decreases.