Ultrasensitive electrochemical cancer cells sensor based on trimetallic dendritic Au@PtPd nanoparticles for signal amplification on lab-on-paper device

Ge, Shenguang; Zhang, Yan; Zhang, Lina; Li, Liang; Liu, Haiyun; Yan, Mei; Huang, Jiadong; Yu, Jinghua

doi:10.1016/j.snb.2015.06.009

Cited by 64 publications

(27 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mean pore diameter distribution of the materials were 9.9, 11.9, and 6.09 for KCC-1, KCC-1-NH 2 , and KCC-1-NH 2 -Cys, respectively (Supporting information Figure S4 (see supporting information)). The pore size, pore volumes, and surface area of KCC-1, KCC-1-NH 2 , and KCC-1-NH 2 -Cys are obviously approved by the reported results [27,29]. Zeta potentials of KCC-1, KCC-1-NH 2 , and KCC-1-NH 2 -Cys were checked at pH 7.5 to determine the surface charge to identify the possible surface modification.…”

Section: Synthesismentioning

confidence: 83%

Synthesize of dendritic fibrous nano-silica functionalized by cysteine and its application as advanced adsorbent

Khantan¹,

Shadjou²,

Hasanzadeh

2019

Nanocomposites

View full text Add to dashboard Cite

L-Cysteine-modified dendritic fibrous nanosilica grafted by amine groups (Cys-DFNS-NH 2 ) have been synthesized by a novel hydrothermal method. The N2 adsorption-desorption isotherms analysis on the Cys-DFNS-NH 2 show that the average pore volume and surface area of the prepared fibrous Cys-DFNS-NH 2 were 2.2 cm 3 /g and 205 m 2 /g, respectively, while the average pore size is 6.06 nm. Adsorption behavior of the Cys-DFNS-NH 2 for Cd 2þ , Cu 2þ , Ag þ , and Pb 2þ was investigated by electrochemical methods. The results show that Cys-DFNS-NH 2 can selectively adsorb Cd 2þ , Ag þ , and Pb 2þ in different potentials. Finally, the application of the engineered adsorbent for the removal of Cd 2þ , Ag þ , and Pb 2þ from contaminated water samples was examined. This work provides a new platform to the synthesis of Cys-DFNS-NH 2 with high specific surface area for efficient adsorbent of specific metal ions. GRAPHICAL ABSTRACT ARTICLE HISTORY

show abstract

Section: Synthesismentioning

confidence: 83%

Synthesize of dendritic fibrous nano-silica functionalized by cysteine and its application as advanced adsorbent

Khantan¹,

Shadjou²,

Hasanzadeh

2019

Nanocomposites

View full text Add to dashboard Cite

show abstract

“…Yu and co‐workers developed a paper microfluidics for detection of cancer cells based on electrochemistry . Au@PdPt nanoparticles with peroxidase‐like catalytic activity were conjugated with folic acid which could bind to K562 cells and the Au‐paper electrode was used as working electrode.…”

Section: Cell Capture/phenotyping On Paper Microfluidic Devicesmentioning

confidence: 99%

“…Folic acid–folate receptor‐based cancer cell capture and detection. Reproduced with permission . Copyright 2015, Elsevier Ltd. B) The schematic diagram of fabrication and operation procedure for the paper‐based electro‐chemiluminescence cyto‐device.…”

Section: Cell Capture/phenotyping On Paper Microfluidic Devicesmentioning

confidence: 99%

Paper Microfluidics for Cell Analysis

Yan

Miao

et al. 2018

Adv Healthcare Materials

View full text Add to dashboard Cite

Paper microfluidics has attracted much attention since its first introduction around one decade ago due to the merits such as low cost, ease of fabrication and operation, portability, and facile integration with other devices. The dominant application for paper microfluidics still lies in point‐of‐care testing (POCT), which holds great promise to provide diagnostic tools to meet the ASSURED criteria. With micro/nanostructures inside, paper substrates provide a natural 3D scaffold to mimic native cellular microenvironments and create excellent biointerfaces for cell analysis applications, such as long‐term 3D cell culture, cell capture/phenotyping, and cell‐related biochemical analysis (small molecules, protein DNA, etc.). This review summarizes cell‐related applications based on various engineered paper microdevices and provides some perspectives for paper microfluidics‐based cell analysis.

show abstract

“…The same authors developed another K-562 cells biosensor on a related origami paper-based platform [39]. The cells were captured by folic acid-functionalized AuNPs grown on the surface of the cellulose fibers, in the paper sample zone of the SPCE.…”

Section: Paper-based Electrochemical Biosensorsmentioning

confidence: 99%

“…Additionally, the stability of the catalytic nanoprobes was improved in comparison with redox enzyme based assays (e.g., horseradish peroxidase, HRP). The sensor also demonstrated good precision and reproducibility with relative standard deviations of intra-assays and inter-assays lower than 5% [39]. …”

Section: Paper-based Electrochemical Biosensorsmentioning

confidence: 99%

Biosensing with Paper-Based Miniaturized Printed Electrodes–A Modern Trend

2016

View full text Add to dashboard Cite

From the bench-mark work on microfluidics from the Whitesides’s group in 2007, paper technology has experienced significant growth, particularly regarding applications in biomedical research and clinical diagnostics. Besides the structural properties supporting microfluidics, other advantageous features of paper materials, including their versatility, disposability and low cost, show off the great potential for the development of advanced and eco-friendly analytical tools. Consequently, paper was quickly employed in the field of electrochemical sensors, being an ideal material for producing custom, tailored and miniaturized devices. Stencil-, inkjet-, or screen-printing are the preferential techniques for electrode manufacturing. Not surprisingly, we witnessed a rapid increase in the number of publications on paper based screen-printed sensors at the turn of the past decade. Among the sensing strategies, various biosensors, coupling electrochemical detectors with biomolecules, have been proposed. This work provides a critical review and a discussion on the future progress of paper technology in the context of miniaturized printed electrochemical biosensors.

show abstract

Ultrasensitive electrochemical cancer cells sensor based on trimetallic dendritic Au@PtPd nanoparticles for signal amplification on lab-on-paper device

Cited by 64 publications

References 44 publications

Synthesize of dendritic fibrous nano-silica functionalized by cysteine and its application as advanced adsorbent

Synthesize of dendritic fibrous nano-silica functionalized by cysteine and its application as advanced adsorbent

Paper Microfluidics for Cell Analysis

Biosensing with Paper-Based Miniaturized Printed Electrodes–A Modern Trend

Contact Info

Product

Resources

About