Ultrasonically guided fine-needle biopsies in neoplastic liver disease: Cytohistologic diagnoses and echo pattern of lesions

Abstract

Sixty consecutive percutaneous fine-needle aspiration biopsies guided by ultrasound were performed without complications in patients with ultrasonically suspected focal or diffuse neoplastic liver disease. Evaluations of aspirated samples were based on cytologic examination of smear preparations (100%) combined with histologic examination of serial sectioned tissue fragments (81.7%). The overall accuracy rate of cytohistologic evaluations was 91.6% with a sensitivity of 92.2%, a specificity of 88.9%, and a high predictive value of positive results (cytology; 97.8%; histology, 100%). Percutaneous fine-needle aspiration biopsy guided by sonography proved to be a safe, useful, and highly accurate technique for making cytohistologic diagnoses of hepatic masses suspected of being malignant. No relationship was found between the various echo patterns of intrahepatic neoplastic lesions and cell type or primary site of tumor origin.

Fine needle aspiration biopsy in pediatric space-occupying lesions of liver: a retrospective study evaluating its role and diagnostic efficacy

“…Fine needle aspiration has a reportedly low complication rate, similar to conventional core biopsies [11]; however, the reported sensitivity in the literature ranges from 67% to 100%, and the specificity ranges from 80% to 100% [4,5,[12][13][14][15]. The various reasons for an incorrect diagnosis include sampling errors, interpretation errors, or poor technical quality of smears.…”

Study of Fine Needle Aspiration Cytology (FNAC) for Diagnosis of Lesions of Liver Diseases Guided By Ultra Sound

“…Other cell types, such as benign or reactive ductular cell and inflammatory cells are more frequently encountered in a benign hepatic proliferation [17,19,21] . In cases of Hepatocellular carcinoma, the predominant and sometimes the only cells present could be those from the tumor.…”

Percutaneous biopsy of abdominal organs under ultrasound guidance

“…Continuous real-time ultrasonographic monitoring of the position of the needle minimises these risks. In addition, the diagnostic yield is maximised as the needle can be placed accurately in the organ of interest, and even in focal lesions within an organ (Schwerk and Schmitz-Moormann 1981).…”