Ultrasound of ovarian sex-cord tumor with annular tubules

Abstract

Sex-cord tumors with annular tubules (SCTAT) have been extensively reported in the literature with great emphasis on the cytologic and histologic appearance. The association of Peutz-Jeghers syndrome (PJS) with bilateral benign, typically multifocal, small, and sometimes calcified SCTAT has also been reported. We present and describe the sonographic findings of bilateral SCTAT in a patient with PJS.

Incidental finding of sex cord tumor with annular tubules in ovary associated with Peutz-Jeghers syndrome

“…[10] Clinical presentations include irregular menstruation, hyperestrinism, the presence of a mass and abdominal/pelvic pain, and in young people there may be sexual precocity. [1,10] The vast majority of patients with SCTAT and PJS also have gastrointestinal polyposis and mucocutaneous melanin pigmentation. [10] Most ovarian SCTAT are benign.…”

“…[1,10] The vast majority of patients with SCTAT and PJS also have gastrointestinal polyposis and mucocutaneous melanin pigmentation. [10] Most ovarian SCTAT are benign. [5] This tumor varies depending on how it presents with PJS.…”

“…[4] Hence, although there is some divergence in the literature, the SCTAT seems to have morphological characteristics intermediate between granulosa cell tumors and Sertoli cell tumors. [1,10] Histologically, this tumor type is characterized by well-circumscribed rounded epithelial nests, simulating an appearance of ring-shaped tubes surrounding hyaline bodies. These nests have two patterns: simple and complex tubular structures, with and without hyaline nuclei.…”

Comprehensive review of imaging features of sex cord-stromal tumors of the ovary

“…On US, they have been reported to be multiple confluent, lobulated echogenic masses or tumorlets (Fig. 5) [44].…”